Drug eruption - Eruzione Da Farmaco
☆ Nei risultati della Stiftung Warentest 2022 dalla Germania, la soddisfazione dei consumatori con ModelDerm è stata solo leggermente inferiore rispetto alle consulenze di telemedicina a pagamento.
Eruzione Da Farmaco (Drug eruption) è caratterizzato dal fatto che colpisce l'intero corpo.
relevance score : -100.0%
ReferencesLe reazioni cutanee causate dai farmaci, note come eruzioni da farmaci, a volte possono essere gravi. Queste reazioni gravi, chiamate severe cutaneous adverse drug reactions (SCARs), sono pericolose per la vita. Includono condizioni come Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP) e drug reaction with eosinophilia and systemic symptoms (DRESS). Sebbene i SCARs siano rari, circa il 2 % dei pazienti ospedalizzati li sperimentano.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Una donna di 31 anni si è recata al reparto di dermatologia con una macchia rossa indolore sulla parte superiore del piede destro. Ha assunto una dose di doxiciclina (100 mg) il giorno prima, dopo il trattamento con laser a picosecondi per le cicatrici da acne. L'anno scorso ha riscontrato un problema simile nello stesso punto dopo aver assunto la stessa dose di doxiciclina post‑laser. Non ha una storia medica significativa e non presenta altri sintomi, come febbre, né localmente né a livello sistemico.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) e toxic epidermal necrolysis (TEN) sono due forme di reazione cutanea grave, diverse da altre condizioni cutanee, come l'eritema multiforme maggiore e la sindrome della pelle ustionata da stafilococco, nonché dalle reazioni ai farmaci. SJS/TEN è una reazione rara e grave che provoca danni diffusi alla pelle e alle mucose, spesso accompagnati da sintomi sistemici. Inoltre, nell’80% dei casi la causa è rappresentata dai farmaci.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Le eruzioni da farmaco vengono diagnosticate principalmente tramite anamnesi e esame clinico; possono essere utili anche una biopsia cutanea, esami del sangue o test immunologici.
Esempi di farmaci comuni che causano eruzioni sono antibiotici e altri farmaci antimicrobici, farmaci sulfamidici, farmaci antinfiammatori non steroidei (FANS), agenti chemioterapici per tumori maligni, anticonvulsivanti e farmaci psicotropi.
○ Diagnosi e trattamento
Se presenti febbre (aumento della temperatura corporea), consulta un medico il prima possibile. Il farmaco sospetto deve essere interrotto (ad esempio antibiotici, farmaci antinfiammatori non steroidei). Prima di recarti in ospedale, gli antistaminici orali come cetirizine (cetirizina) o loratadine (loratadina) possono alleviare prurito ed eruzione cutanea.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Esame del sangue (CBC, LFT, conta degli eosinofili)
Steroidi e antistaminici orali su prescrizione medica