Staphylococcal scalded skin syndrome - Sindrome Della Pelle Spellata Stafilococcica
☆ Nei risultati della Stiftung Warentest 2022 dalla Germania, la soddisfazione dei consumatori con ModelDerm è stata solo leggermente inferiore rispetto alle consulenze di telemedicina a pagamento.
Un neonato con Sindrome Della Pelle Spellata Stafilococcica (Staphylococcal scalded skin syndrome)
References
Staphylococcal Scalded Skin Syndrome è una condizione in cui la pelle perde pelo a causa delle tossine prodotte da alcuni tipi di batteri Staphylococcus. È raro nei bambini sopra i sei anni. Può verificarsi anche negli adulti con sistema immunitario indebolito o gravi problemi renali. La caratteristica principale è un'estesa desquamazione della pelle a seguito dell'infiammazione. La gravità varia da poche vesciche a una diffusa perdita di pelle, che può causare gravi cali della temperatura corporea e instabilità della pressione sanguigna.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
Un bambino di 10 mesi è entrato con il naso che cola e non mangiava bene. I medici dissero che si trattava di un'infezione delle vie respiratorie superiori. Due giorni dopo è tornato perché non migliorava e aveva nuovi problemi come viso gonfio e pelle irritata intorno alla bocca. Nei due giorni successivi il ragazzo peggiorò. Le sue braccia e le sue gambe si gonfiarono e la sua pelle cominciò a staccarsi. Tornati in ospedale, i medici hanno notato un'eruzione cutanea rossa sul viso e nelle pieghe della pelle, che sbiancava al tatto. Gli hanno diagnosticato staphylococcal scalded skin syndrome (SSSS) e gli hanno iniziato la cura con antibiotici attraverso una vena.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
Una bambina di 2 anni si è presentata con un'eruzione cutanea su tutto il corpo che si era sviluppata nell'arco di 48 ore, in seguito a punture di insetti sul viso il giorno prima. Durante l'esame, presentava un'eruzione cutanea diffusa, composta da piccole protuberanze che si fondevano insieme e, se leggermente strofinata, la sua pelle mostrava segni del segno di Nikolsky. Non c'erano segni di eruzione cutanea che colpisse le sue mucose. Gli esami del sangue non hanno mostrato alcun segno di infezione.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
La sindrome è indotta dalle esotossine epidermolitiche (esfoliatina) A e B, che vengono rilasciate dallo S. aureus. La prognosi della sindrome della pelle spellata stafilococcica (staphylococcal scalded skin syndrome) nei bambini è eccellente, con risoluzione completa entro 10 giorni dal trattamento e senza cicatrici significative. Tuttavia, la sindrome della pelle spellata stafilococcica (staphylococcal scalded skin syndrome) deve essere attentamente differenziata dalla necrolisi epidermica tossica, che comporta una prognosi infausta.
○ Diagnosi e trattamento
La diagnosi errata di lesioni da eczema come la dermatite atopica e l'applicazione di unguenti steroidei aggravano le lesioni. Si prega di consultare un medico il prima possibile durante l'applicazione della pomata antibiotica.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)