Alopecia areata - 円形脱毛症
円形脱毛症 (Alopecia areata) は頭皮の裏側に見られます。典型的な場合、それは突然完全に滑らかな表面で2〜3 cmの大きさで現れます。
References
Alopecia areata は、免疫システムが毛包を攻撃し、瘢痕を残さずに一時的な脱毛を引き起こす症状です。それは斑点状の脱毛として現れることもあれば、頭皮や体全体に影響を与えることもあり、人生のある段階で約 2% の人々に影響を及ぼします。主な原因は、毛包周囲の自然な保護機能の破壊であるようです。
Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type. Alopecia areata affects nearly 2% of the general population at some point during their lifetime. A breakdown of immune privilege of the hair follicle is thought to be an important driver of alopecia areata.
Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type. Alopecia areata affects nearly 2% of the general population at some point during their lifetime. A breakdown of immune privilege of the hair follicle is thought to be an important driver of alopecia areata.
Alopecia areata は、免疫システムが毛包を攻撃し、頭皮や体の他の毛深い部分に脱毛を引き起こす症状です。世界中の約 2% の人々が罹患しています。どの年齢でも発生する可能性がありますが、成人よりも小児に多く見られます (1. 92% vs. 1. 47%) 。女性、特に50歳以上の女性は男性よりもこの症状を経験する傾向があります。 コルチコステロイドを局所的に塗布するよりも、患部に直接注射する方が良い結果が得られています。
Alopecia areata is an immune-mediated condition leading to non-scarring alopecia of the scalp and other hair-bearing areas of the body. It affects up to 2% of the global population. It can affect all ages, but the prevalence appears higher in children compared to adults (1.92%, 1.47%). A greater incidence has been reported in females than males, especially in patients with late-onset disease, defined as age greater than 50 years. Intralesional injection of corticosteroids has been reported to lead to better responses compared to topical steroids.
Alopecia areata is an immune-mediated condition leading to non-scarring alopecia of the scalp and other hair-bearing areas of the body. It affects up to 2% of the global population. It can affect all ages, but the prevalence appears higher in children compared to adults (1.92%, 1.47%). A greater incidence has been reported in females than males, especially in patients with late-onset disease, defined as age greater than 50 years. Intralesional injection of corticosteroids has been reported to lead to better responses compared to topical steroids.
円形脱毛症は、毛包の免疫系に関連する自己免疫疾患であると考えられています。根底にあるメカニズムには、身体が自身の細胞を認識できなくなり、その後の免疫介在による毛包の破壊が含まれます。
○ 治療 ― OTC医薬品
軽度の円形脱毛症の場合、治療を受けなくても 1 年以内に回復する人もいます。しかし、ほとんどの人は頭皮上のランダムな部位で再発を経験します。
#Hydrocortisone cream
○ 処理
病変内ステロイド注射が最も効果的な治療法です。頭皮の広範囲が影響を受けている場合は、免疫療法を試すことができます。
#Triamcinolone intralesional injection
#DPCP immunotherapy