Grover disease - Grover 病
Grover 病 (Grover disease) は、胴体にかゆみを伴う赤い斑点として突然現れる症状で、多くの場合は高齢の男性に見られます。
References
一過性表皮溶解性皮膚炎としても知られる Grover disease は、主に年配の白人男性に見られる、体液で満たされた隆起として現れる発疹です。かゆみを伴うことがよくありますが、長くは続きません。 Grover disease には 4 つの異なるパターンの組織変化があり、血液がんなどのさまざまな病気と関連しています。自然に現れたり消えたりする傾向があるため、追跡して治療するのが難しい場合があります。 Grover disease は他の皮膚科的および非皮膚科的皮膚疾患と頻繁に関連しているため、造血器悪性腫瘍を含む他の併発疾患を除外することが不可欠です。
Grover disease, also known as transient acantholytic dermatosis, is a rash that appears as bumps filled with fluid on the upper body, mainly in older white men. It's often itchy but doesn't last long. There are 4 different patterns of tissue changes in Grover disease, and it has been linked to various illnesses, like blood cancers. It can be hard to track and treat because it tends to come and go on its own. Because Grover disease has been associated frequently with other dermatologic and nondermatologic skin conditions, to rule out other concomitant disorders, including hematopoietic malignancies is essential.
Grover disease, also known as transient acantholytic dermatosis, is a rash that appears as bumps filled with fluid on the upper body, mainly in older white men. It's often itchy but doesn't last long. There are 4 different patterns of tissue changes in Grover disease, and it has been linked to various illnesses, like blood cancers. It can be hard to track and treat because it tends to come and go on its own. Because Grover disease has been associated frequently with other dermatologic and nondermatologic skin conditions, to rule out other concomitant disorders, including hematopoietic malignancies is essential.
この報告では、過去 3 ～ 4 か月間胸に発疹があった 80 歳の白人男性の Grover's disease の稀な症例について説明します。彼には、高血圧、高コレステロール、膝関節炎、慢性酸逆流、心拍数の上昇、前立腺がんの既往歴、レストレスレッグス症候群の既往歴があります。初めは上半身を中心にかゆみのある赤くデコボコした発疹が出ていました。さまざまなクリームやローションを使用しましたが、症状はあまり改善されませんでした。皮膚科を受診し、皮膚生検を受けた結果、 Grover's disease の診断が確定しました。その後、ステロイドクリームによる治療を２週間受けた。
This case report details a rare case of Grover's disease in an 80-year-old Caucasian male complaining of a rash across his chest over the last three to four months. The patient has a past medical history of essential hypertension, hyperlipidemia, osteoarthritis of the knee, chronic gastroesophageal reflux disease (GERD), supraventricular tachycardia, status post prostate cancer, and restless legs syndrome. During his initial evaluation, he was found to have a pruritic, erythematous, papular rash most notably along his upper trunk and chest. The patient utilized multiple lotions, emollients, and anti-itch creams with minimal relief of his symptoms and presentation. Following a referral to Dermatology, a biopsy of the rash was conducted, which revealed intraepidermal acantholysis, the hallmark finding for a diagnosis of Grover's disease. Subsequently, he was treated with a topical triamcinolone acetonide 0.1% cream for 14 days.
This case report details a rare case of Grover's disease in an 80-year-old Caucasian male complaining of a rash across his chest over the last three to four months. The patient has a past medical history of essential hypertension, hyperlipidemia, osteoarthritis of the knee, chronic gastroesophageal reflux disease (GERD), supraventricular tachycardia, status post prostate cancer, and restless legs syndrome. During his initial evaluation, he was found to have a pruritic, erythematous, papular rash most notably along his upper trunk and chest. The patient utilized multiple lotions, emollients, and anti-itch creams with minimal relief of his symptoms and presentation. Following a referral to Dermatology, a biopsy of the rash was conducted, which revealed intraepidermal acantholysis, the hallmark finding for a diagnosis of Grover's disease. Subsequently, he was treated with a topical triamcinolone acetonide 0.1% cream for 14 days.
