Lymphangioma - リンパ管腫
リンパ管腫 (Lymphangioma) は、薄壁の嚢胞様病変を特徴とするリンパ系の奇形です。これらの奇形はあらゆる年齢で発生し得ますが、90% は 2 歳未満の小児に見られ、特に頭頸部に多く発生します。リンパ管腫は通常、胎児超音波検査により出生前に診断されます。後天性リンパ管腫は外傷、炎症、またはリンパ管閉塞が原因で生じることがあります。悪性化しないため、治療は主に美容上の理由で行われます。
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ドイツの2022年Stiftung Warentestの結果では、ModelDermに対する消費者満足度は有料の遠隔医療相談よりもわずかに低いだけでした。
ドイツの2022年Stiftung Warentestの結果では、ModelDermに対する消費者満足度は有料の遠隔医療相談よりもわずかに低いだけでした。
relevance score : -100.0%
ReferencesLymphangioma はリンパ奇形 (LM) としても知られています。先天性の血管障害で、出生前後のリンパ組織の異常な増殖が特徴です。Lymphangioma は約 2000 ～ 4000 人に 1 人が罹患し、性別や人種による大きな差はありません。ほとんどの症例 (80 ～ 90%) は 2 歳までに診断されます。症状は局所的な腫れからリンパ管の広範囲にわたる異常まで多岐にわたり、時には象皮病として知られる重度の腫れにつながることもあります。 たとえば、首や顔にできた lymphangioma は顔面の腫れを引き起こし、重症例では外観を損なうことがあります。舌に影響を与えると、顎の過成長や歯並びの乱れを招く可能性があります。口や首に発生すると、呼吸障害や生命を脅かす緊急事態を引き起こすことがあります。眼にできると、視力低下、眼球運動制限、眼瞼下垂、眼球突出などを招くことがあります。四肢にできると、組織や骨の腫脹や異常な成長を引き起こすことがあります。 この腫瘍は通常ゆっくりと成長しますが、感染症やホルモン変化、外傷により急速に拡大することがあり、生命を脅かす緊急治療が必要になるリスクがあります。
Lymphangioma (lymphatic malformation, LM), a congenital vascular disease, is a low-flow vascular abnormality in lymphatic diseases that is characterized by excessive growth of lymphatic tissue during prenatal and postpartum development. The incidence rate of LM is ~1:2000–4000, with no variation between genders and races. Most patients (80–90%) are diagnosed before the age of two. The clinical manifestations of lymphangioma are quite different among patients, varying from local swelling leading to superficial mass to a large area of diffuse infiltrating lymphatic channel abnormalities resulting in elephantiasis. Cervicofacial LM can cause facial elephantiasis, and in some severe cases, it can lead to serious disfigurement of the face. Tongue LM can lead to mandibular overgrowth and occlusal asymmetry, and oral and cervical LM can cause obstructive acute respiratory distress and life-threatening situations. Orbital LM may lead to decreased vision, decreased extraocular muscle movement, ptosis and exophthalmos. LM of the extremities can trigger swelling or gigantism, accompanied by overgrowth of soft tissue and bones. LM usually grows slowly and steadily, but under certain conditions, such as infection, hormonal changes or trauma, it can grow explosively and become a life-threatening disease requiring immediate treatment.
Lymphangioma (lymphatic malformation, LM), a congenital vascular disease, is a low-flow vascular abnormality in lymphatic diseases that is characterized by excessive growth of lymphatic tissue during prenatal and postpartum development. The incidence rate of LM is ~1:2000–4000, with no variation between genders and races. Most patients (80–90%) are diagnosed before the age of two. The clinical manifestations of lymphangioma are quite different among patients, varying from local swelling leading to superficial mass to a large area of diffuse infiltrating lymphatic channel abnormalities resulting in elephantiasis. Cervicofacial LM can cause facial elephantiasis, and in some severe cases, it can lead to serious disfigurement of the face. Tongue LM can lead to mandibular overgrowth and occlusal asymmetry, and oral and cervical LM can cause obstructive acute respiratory distress and life-threatening situations. Orbital LM may lead to decreased vision, decreased extraocular muscle movement, ptosis and exophthalmos. LM of the extremities can trigger swelling or gigantism, accompanied by overgrowth of soft tissue and bones. LM usually grows slowly and steadily, but under certain conditions, such as infection, hormonal changes or trauma, it can grow explosively and become a life-threatening disease requiring immediate treatment.
この後ろ向き研究では、1999 年 1 月から 2004 年 12 月までに lymphangioma (リンパ管腫) を患い、Bleomycin (ブレオマイシン) 溶液の注射による治療を受けた 24 人の子供を調査しました。病変の大部分（63%）は完全に消失し、21% は良好な反応を示し、残りの 16% は十分な反応が得られませんでした。2 人の患者は後に腫瘍が再発し、別の 2 人は注射部位に膿瘍ができました。幸いなことに、他に大きな問題や副作用は認められませんでした。
This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.
This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.
Lymphangioma の主な種類は次のとおりです：lymphangioma circumscriptum、cavernous lymphangioma、cystic hygroma、lymphangioendothelioma。これらは小児の良性血管腫瘍の約 26 % を占めますが、成人ではあまり一般的ではありません。lymphangioma circumscriptum は最も頻度の高いタイプで、皮膚から突き出たリンパ管が認められ、カエルの卵に似た透明な液体で満たされた小胞が形成され、組織が腫れています。通常、手足、体幹、脇の下など、リンパネットワークが豊富な領域に発生します。71 歳の女性が、持続する脚の腫れ、性器のピンク色の隆起、かゆみ、リンパ液の漏出を訴えて来院しました。私たちは、クリトリスと四シェットを温存しながら、コーレス筋膜レベルで止める両側大陰唇切除術という手術で、すべての隆起を外科的に除去しました。
The predominant types of lymphangioma are lymphangioma circumscriptum (LC), cavernous lymphangioma, cystic hygroma, and lymphangioendothelioma. These entities account for approximately 26% of benign vascular tumors in children but are rarer in adults. LC is the most common form of cutaneous lymphangioma and is characterized by superficial lymphatic ducts protruding through the epidermis. This condition results in clusters of clear fluid-filled vesicles resembling frog spawn and associated tissue edema. It is usually found on the proximal extremity, trunk, and axilla, which has an abundant lymphatic system. A 71-year-old female presented to our outpatient clinic with persistent edema of both lower limbs, clusters of pink labial papules, pruritus, and watery lymph oozing. We removed all the papules by performing bilateral major labiectomy down to the level of Colles' fascia, sparing the clitoris and fourchette.
The predominant types of lymphangioma are lymphangioma circumscriptum (LC), cavernous lymphangioma, cystic hygroma, and lymphangioendothelioma. These entities account for approximately 26% of benign vascular tumors in children but are rarer in adults. LC is the most common form of cutaneous lymphangioma and is characterized by superficial lymphatic ducts protruding through the epidermis. This condition results in clusters of clear fluid-filled vesicles resembling frog spawn and associated tissue edema. It is usually found on the proximal extremity, trunk, and axilla, which has an abundant lymphatic system. A 71-year-old female presented to our outpatient clinic with persistent edema of both lower limbs, clusters of pink labial papules, pruritus, and watery lymph oozing. We removed all the papules by performing bilateral major labiectomy down to the level of Colles' fascia, sparing the clitoris and fourchette.
