Acne - Kukul
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Jerawat ing wilayah awak. Sisih ndhuwur lan mburi awak minangka area umum kanggo kukul.
relevance score : -100.0%
ReferencesJerawat, kondisi kulit sing paling umum ing Amerika Serikat, minangka masalah kulit inflamasi sing kronis. Perawatan ditujokake kanggo ngatasi patang faktor utama sing nyebabake kukul: produksi sebum sing berlebihan, penumpukan sel kulit, kolonisasi Propionibacterium acnes, lan inflamasi. Retinoid topikal efektif ngatur lesi inflamasi lan non‑inflamasi kanthi nyegah lan nyuda komedo, lan uga ngurangi inflamasi. Benzoyl peroksida, sing kasedhiya over‑the‑counter, minangka agen bakterisida tanpa nambah resistensi bakteri. Nalika antibiotik topikal lan lisan digunakake dhewe, kombinasi karo retinoid topikal nambah efektifitas. Nambahake benzoyl peroksida ing terapi antibiotik nyuda risiko resistensi bakteri. Isotretinoin lisan, disetujoni kanggo kukul abot lan bandel, diwenehake liwat program iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Pangobatan topikal umum kanggo kukul kalebu benzoyl peroxide (BP), salicylic acid, antibiotik, kombinasi antibiotik karo BP, retinoid, kombinasi retinoid karo BP utawa antibiotik, azelaic acid, lan sulfone agents. Antibiotik oral wis suwe dadi bagéan penting saka perawatan kukul, utamané kanggo kasus moderat nganti abot. Obat iki paling efektif yen digunakaké bebarengan karo retinoid topikal lan BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, lan cephalexin kabeh wis nuduhaké bukti efektifitas.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Retinoid topikal tansah dianjurake kanggo nambani kukul. Nalika nggunakake antibiotik sistemik utawa topikal, penting kanggo nggabungake karo benzoyl peroksida lan retinoid, nanging ora luwih saka 12 minggu. Isotretinoin dilindhungi undhang‑undhang kanggo kasus kukul abot sing durung nanggapi perawatan liyane. Sanajan ana sawetara bukti kanggo perawatan fisik kayata terapi laser lan kulit kimia, uga pendekatan pelengkap kayata racun tawon sing dimurnikan lan diet tartamtu, efektivitasé isih durung pasti.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Sawetara panaliten wis nyinaoni kepiye macem‑macem panganan mengaruhi kukul ing pasien. Panalitèn kasebut nemokake manawa wong sing duwe kukul lan mangan panganan kanthi beban glikemik sing sithik cenderung nduwèni bintik‑bintik kukul luwih sithik dibandhingake karo sing mangan panganan kanthi beban glikemik sing dhuwur. Susu uga wis diteliti babagan kukul. Katon manawa protein tartamtu ing susu bisa nyebabake kukul luwih akeh tinimbang isi lemak utawa susu sakabèhé. Riset liyane fokus ing asam lemak omega‑3 lan asam γ‑linoleat. Iki nuduhake manawa wong sing duwe kukul bisa entuk manfaat saka mangan luwih akeh iwak lan lenga sehat kanggo nambah asupan asam lemak kasebut. Panaliten anyar babagan probiotik kanggo kukul nuduhake asil sing janjeni, nanging riset luwih akeh dibutuhake kanggo ngonfirmasi temuan awal kasebut.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Ing loro jinis, hormon androgen dadi bagéan penting saka mekanisme dhasar, amarga nambah produksi sebum. Faktor umum liyane yaiku pertumbuhan bakteri Cutibacterium acnes ing kulit.
Pangobatan topikal sing langsung ditrapake ing kulit sing kena, kayata asam azelaic, benzoyl peroxide, lan asam salisilat, umume digunakake. Antibiotik lan retinoid uga kasedhiya ing formulasi topikal lan oral kanggo perawatan kukul. Nanging, resistensi antibiotik bisa berkembang akibat terapi antibiotik sing suwe. Sawetara pil KB (kontrasepsi oral) bisa mbantu nyegah kukul ing wanita. Perawatan awal lan agresif nganggo isotretinoin bisa nyuda komplikasi jangka panjang.
○ Pengobatan
Gel Adapalene bisa digunakake sacara wiyar amarga nyuda sekresi sebum lan ngurangi kambuhé kukul. Nanging, yen kakehan ditrapake ing wiwitan, gel iki bisa ngganggu kulit. Benzoyl peroxide lan asam azelaic, ing sisih liya, efektif kanggo lesi inflamasi amarga nduwèni sifat anti‑inflamasi. Umumé, perawatan jangka panjang paling ora 1 wulan dibutuhake kanggo ndeleng asil sing jelas.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction