Angiofibroma
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ReferencesCutaneous angiofibromas bisa katon ing macem‑macam bagean awak. Ing pasuryan, asring dikenal minangka fibrous papule utawa adenoma sebaceum; ing penis, diarani pearly penile papules; ing ngisor kuku, diarani periungual angiofibroma utawa Koenen tumor; lan ing tutuk, diarani fibromas lisan (oral fibromas). Facial angiofibroma (facial angiofibroma) minangka fitur penting saka tuberous sclerosis (TS), kelainan warisan sing mengaruhi kulit, ginjel, jantung, otak, lan paru‑paru. Biasane berkembang ing pasuryan nalika bocah cilik utawa awal diwasa ing individu kanthi TS. Duwe telu utawa luwih facial angiofibroma utawa loro utawa luwih periungual angiofibroma dianggep penting kanggo diagnosa TS. Kajaba iku, sawetara facial angiofibroma bisa uga ana ing kahanan multiple endocrine neoplasia type 1 (MEN‑1) lan Birt‑Hogg‑Dubé syndrome. Pearly penile papules ditemokake ing pinggir koronal lan sulkus penis. Iki minangka benjolan sing terus‑terusan, ora krasa lara, luwih umum katon ing wong sing ora disunat.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) pasuryan
Fibrous papule
2) penis
Pearly penile papule
3) ing ngisor kuku utawa kuku jempol
Periungual angiofibroma