Dysplastic nevus - Nevus Displastik
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Dysplastic nevi ― Biopsi dianjurake kanggo wong kulon.
relevance score : -100.0%
ReferencesDysplastic nevus, uga dikenal minangka atypical utawa Clark's nevus, wis nyebabake debat ing dermatologi lan dermatopatologi. Dokter asring nindakake biopsi moles iki amarga bisa katon ora normal lan nambah keprihatinan babagan melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi, uga dikenal minangka atipikal utawa Clark nevi, kadhangkala bisa nyebabake melanoma. Udakara 36 % melanoma ditemokake cedhak nevi dysplastic. Tandha manawa nevi dysplastic bisa dadi melanoma kalebu wujud sing ora rata, owah‑owahan pigmen sing luwih akeh, utawa werna abu‑abu. Kanker iki biasane kedadeyan ing umur sing luwih enom (kira‑kira pertengahan telung puluhan), bisa dadi pirang‑pirang, lan asring ana ing batang. Secara genetis, dysplastic nevi ana ing antarane nevi jinak lan melanoma. Nanging, mung 20 % nganti 30 % melanoma asale saka nevi sing ana. Amarga umume nevi ora dadi melanoma, biasane ora dianjurake kanggo mbusak kanthi pencegahan.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Melanoma yaiku jinis tumor sing dibentuk nalika melanosit, sel sing tanggung jawab kanggo warna kulit, dadi kanker. Melanosit asalé saka sel puncak saraf. Iki tegese melanoma bisa berkembang ora mung ing kulit, nanging uga ing wilayah liya ing ngendi sel‑sel puncak saraf migrasi, kayata saluran pencernaan lan otak. Tingkat kelangsungan urip kanggo pasien melanoma tahap awal (tahap 0) dhuwur, nganti 97 %, nanging mudhun sacara signifikan nganti udakara 10 % kanggo wong sing didiagnosa ing tahap lanjut (tahap IV).
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Risiko Kanker
Kaya sing katon ing wong Kaukasia ing Amerika Serikat, wong sing duwe nevi dysplastic duwe risiko seumur hidup kanggo ngembangake melanoma luwih saka 10 %. Ing sisih liya, wong sing ora duwe nevus dysplastic duwe risiko ngembangake melanoma kurang saka 1 %.
○ Pencegahan kanggo wong sing duwe nevi displastik
Pemeriksaan diri kulit biasane dianjurake kanggo nyegah melanoma (kanthi ngenali nevi atipikal sing bisa dicopot) utawa kanggo ndeteksi tumor kanthi awal. Wong sing duwe riwayat kanker kulit pribadi utawa kulawarga, utawa sing duwe akèh nevi atipikal, kudu ndeleng dokter kulit paling ora setaun sepisan supaya dipastikan ora ana melanoma.
Singkatan [ABCDE] migunani kanggo mbantu panyedhiya perawatan kesehatan lan wong awam ngelingi karakteristik utama melanoma. Sayangé, kanggo wong rata-rata, akèh keratosis seborrheic, sawetara lentigo senilis, lan malah warts bisa nduwèni ciri [ABCDE] lan ora gampang dibédakaké saka melanoma.
○ [ABCDE]
Asymmetrical: Lesi kulit asimetris.
Border: Wates lesi ora teratur.
Color: Melanoma biasane nduwèni pirang-pirang warna sing ora seragam.
Diameter: Nevi sing luwih gedhe tinimbang 6 mm luwih cenderung dadi melanoma tinimbang nevi sing luwih cilik.
Evolution: Evolusi (yaiku owah‑owahan) saka nevus utawa lesi bisa nuduhaké yèn lesi kasebut dadi ganas.