Hidradenitis suppurativahttps://en.wikipedia.org/wiki/Hidradenitis_suppurativa
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References What is hidradenitis suppurativa? 28209676 NIH
Hidradenitis suppurativa minangka kondisi kulit sing kronis, terus bali, lan bisa mengaruhi urip sampeyan. Iki disebabake inflamasi ing folikel rambut, lan asring nyebabake infeksi bakteri. Dokter biasane diagnosa kanthi ndeleng jinis lara sing sampeyan nandhang (kayata nodul, abses, utawa saluran sinus) , ing endi (biasane ing lipatan kulit) , lan sepira kerepe dheweke bali lan suwene tetep.
Hidradenitis suppurativa is a chronic, recurrent, and debilitating skin condition. It is an inflammatory disorder of the follicular epithelium, but secondary bacterial infection can often occur. The diagnosis is made clinically based on typical lesions (nodules, abscesses, sinus tracts), locations (skin folds), and nature of relapses and chronicity.
Medical Management of Hidradenitis Suppurativa with Non-Biologic Therapy: What’s New? 34990004 NIH
Pangobatan non-biologis lan non-prosedural umume digunakake kanggo penyakit entheng lan bisa digabungake karo terapi biologis lan operasi kanggo penyakit moderat nganti abot. Pasinaon anyar nyedhiyakake bukti tambahan babagan efektifitas kanggo nggunakake kortikosteroid sing disuntikake langsung menyang lesi kanggo HS flare-up lan lesi lokal. Salajengipun, ana bukti sing nuduhake yen nggunakake tetracyclines mung bisa efektif kaya nggabungake clindamycin karo rifampicin.
Non-biologic and non-procedural treatments are often used as monotherapy for mild disease and can be used in conjunction with biologic therapy and surgery for moderate to severe disease. Recent studies highlighted in this review add support for the use of intralesional corticosteroids for HS flares and localized lesions, and there is evidence that monotherapy with tetracyclines may be as effective as the clindamycin/rifampicin combination.
Hidradenitis Suppurativa: A Systematic Review and Meta-analysis of Therapeutic Interventions 30924446Akeh perawatan sing digunakake kanggo hidradenitis suppurativa, kalebu antibiotik, retinoid, antiandrogen, obat sing nyuda kekebalan, obat anti-inflamasi, lan radioterapi kanggo lesi awal. Pangobatan sing paling disaranake yaiku adalimumab lan terapi laser. Pembedahan, salah siji eksisi prasaja utawa eksisi lokal lengkap kanthi grafting kulit, minangka pilihan sing luwih disenengi kanggo kasus sing abot lan lanjut sing ora nanggapi perawatan liyane.
Many treatments are used for hidradenitis suppurativa, including antibiotics, retinoids, antiandrogens, immune-suppressing drugs, anti-inflammatory medications, and radiotherapy for early lesions. The top recommended treatments are adalimumab and laser therapy. Surgery, either simple excision or complete local excision with skin grafting, is the preferred option for severe, advanced cases that don't respond well to other treatments.
Panyebab sing tepat biasane ora jelas, nanging dipercaya kalebu kombinasi faktor genetik lan lingkungan. Udakara sapratelune wong sing nandhang penyakit kasebut duwe anggota kulawarga sing kena pengaruh. Faktor risiko liyane kalebu obesitas lan ngrokok. Kondisi kasebut ora disebabake infeksi, kebersihan sing ora apik.
Ora ana tamba sing dingerteni. Mbukak lesi kanggo ngidinake saluran ora entuk manfaat sing signifikan. Nalika antibiotik umume digunakake, bukti panggunaane kurang. Pengobatan imunosupresif uga bisa dicoba. Ing wong sing nandhang penyakit sing luwih abot, terapi laser utawa operasi kanggo mbusak kulit sing kena pengaruh bisa uga bisa ditindakake. Arang banget, lesi kulit bisa berkembang dadi kanker kulit.
Yen kasus ringan saka hidradenitis suppurativa kalebu, mula perkiraan frekuensi saka 1-4% saka populasi. Wanita kaping telu luwih cenderung didiagnosis tinimbang wong lanang. Onset biasane ing diwasa enom.