Juvenile xanthogranuloma - Xanthogranuloma Remaja
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References
Juvenile xanthogranuloma (JXG) minangka kondisi sing cukup umum lan jinis non-Langerhans cell histiocytic disorder sing paling umum ing bocah-bocah. Ing udakara 75% kasus, lesi kasebut katon ing taun pisanan urip, lan luwih saka 15-20% pasien ngalami wiwit lair. Nalika langka ing wong diwasa, JXG biasane ana paling asring ing wong ing pungkasan rong puluhan kanggo telung puluhan, lan paling patients diwasa mung siji lesi. Secara klinis, katon minangka gumpalan utawa gumpalan kuning-oranye-coklat siji utawa pirang-pirang, utamane ing pasuryan, gulu, lan awak ndhuwur. Lesi lisan ora umum nanging bisa katon minangka gumpalan kuning ing pinggir ilat utawa ing papan liya ing tutuk, bisa uga nyebabake ulkus lan getihen. Lesi kulit biasane ora nyebabake gejala lan cenderung ilang dhewe sajrone pirang-pirang taun. Sanajan langka, keterlibatan okular minangka masalah sing paling umum ngluwihi kulit, banjur keterlibatan paru-paru. Ocular JXG biasane mung kena siji mripat lan kedadeyan kurang saka 0. 5 % pasien, sanajan udakara 40% sing nandhang keterlibatan okular uga duwe pirang-pirang lesi kulit nalika didiagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranulomas (JXGs) ora umum, penyakit jinak sing kalebu ing kategori non-Langerhans cell histiocytoses sing luwih gedhe. Biasane katon minangka siji utawa luwih gumpalan abang utawa kuning, asring ditemokake ing sirah utawa gulu. Umume JXG berkembang nalika lair utawa ing taun pisanan urip. Sanadyan ora umum, kadhangkala bisa nyebabake wilayah sing ngluwihi kulit, kanthi keterlibatan mata minangka perkara sing kudu diawasi miturut literatur sing ana. Umume, JXG ing kulit ilang dhewe lan biasane ora mbutuhake perawatan.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Lesi okular diwujudake ing nganti 10% wong sing duwe JXG lan bisa nyebabake penglihatan. Senadyan lesi kulit biasane ilang kanthi spontan, lesi okular arang saya apik kanthi spontan lan mbutuhake perawatan.