Melasmahttps://en.wikipedia.org/wiki/Melasma
Melasma yaiku warna kulit sing peteng utawa peteng ing pasuryan. Melasma dianggep disebabake dening cahya srengenge, predisposisi genetik, owah-owahan hormon, lan iritasi kulit. Sanajan bisa mengaruhi sapa wae, umume umume ing wanita, utamane wanita ngandhut lan sing nggunakake kontrasepsi utawa obat terapi penggantian hormon.

Melasma ora bisa dirampungake kanthi perawatan laser sajrone wektu tartamtu, amarga iki minangka penyakit sing terus-terusan ngasilake pigmen. Asam tranxenemic mbantu nyuda pigmentasi.

Pengobatan
Ing sawetara negara (kayata Jepang, Korea), asam traneksamat lisan kasedhiya liwat counter lan efektif. Krim melasma kanthi asam traneksamat lan asam azelaat bisa uga migunani.
Hydroquinone bisa digunakake sacara topikal kanggo perawatan hiperpigmentasi, nanging FDA mandhegake produk OTC sing ngemot hydroquinone ing taun 2020.
#Tranexamic acid [TRANSINO]

#Laser toning technique (low fluence QS1064 laser)
#Triluma
☆ Ing asil Stiftung Warentest 2022 saka Jerman, kepuasan konsumen karo ModelDerm mung luwih murah tinimbang konsultasi telemedicine sing dibayar.
  • Iku kondisi umum diamati ing wanita Asia ing awal 40s. Lesi bunder ing foto luwih cedhak karo lentigo tinimbang melasma.
    References Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review 28374042
    Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
     The Low-Fluence Q-Switched Nd:YAG Laser Treatment for Melasma: A Systematic Review 35888655 
    NIH
    Bubar, low-fluence Q-switched Nd:YAG (LFQSNY) laser wis dadi populer kanggo nambani melasma, utamané ing Asia. Nyimpulake macem-macem pasinaon dadi tantangan, nanging LFQSNY katon umume efektif lan aman kanggo melasma dibandhingake karo terapi tradisional. Nanging, sawetara kasus hipopigmentasi mottled wis dilaporake minangka efek samping saka LFQSNY, bisa uga amarga energi laser sing dhuwur. Panggunaan agresif LFQSNY uga bisa nyebabake hiperpigmentasi saka inflamasi, utamane ing warna kulit sing luwih peteng.
    Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
     Pigmentation Disorders: Diagnosis and Management 29431372
    Masalah pigmentasi asring ditemokake ing perawatan primer. Jinis umum kelainan hiperpigmentasi kalebu post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
    Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.