informasi liyane ― Wong jawa

Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.

Panniculitis mbentuk klompok heterogen saka penyakit inflamasi sing nyangkut jaringan adipose subkutan. Kelainan iki arang banget ing bocah-bocah. Panniculitis bisa dadi proses utama ing kelainan sistemik utawa proses sekunder sing disebabake infeksi, trauma utawa paparan obat. Umume jinis panniculitis duwe presentasi klinis sing padha (tanpa preduli saka etiologi) , kanthi nodul subkutan erythematous sing lembut.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.

Panniculitis , inflamasi lemak subkutan, biasane ana karo nodul inflamasi. Erythema nodosum (EN) sacara klinis minangka wangun panniculitis sing paling kerep. Nalika nganti 55% EN dianggep idiopatik, panyebab sing paling umum kalebu infeksi, obat-obatan, penyakit sistemik kayata sarcoidosis lan penyakit radang usus, meteng, lan ganas. EN biasane ana ing remaja lan 20-an, lan katon luwih umum ing wanita. Asring didhisiki dening prodrome non-spesifik saka siji nganti telung minggu, sing bisa uga kalebu demam, malaise, lan gejala infeksi saluran napas ndhuwur. Lesi kulit banjur ngetutake, biasane dilokalisasi ing aspek ekstensor anggota awak. Lesi kasebut nglarani bunder utawa oval, rada mundhak, nodul abang non-ulseratif. Patogenesis sing tepat saka EN ora dimangerteni, sanajan dianggep minangka asil saka deposisi kompleks imun ing venula septae ing lemak subkutan, nyebabake panniculitis neutrofilik. Sanajan tanpa terapi khusus kanggo kondisi sing nyebabake, EN bisa rampung tanpa perawatan ing pirang-pirang kasus.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.