Syphilis - Sipilis
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Chancres ― infeksi syphilitic primer dening Treponema pallidum
References
Sifilis minangka penyakit kelamin sing disebabake dening bakteri Treponema pallidum. Ing panliten iki, kita fokus ing 57 pasien umur 18-68 karo sifilis sekunder.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Sifilis minangka infeksi bakteri sing disebabake dening Treponema pallidum. Bisa niru macem-macem penyakit, entuk julukan great imitator. Sifilis isih kena pengaruh jutaan ing saindenging jagad nanging bisa diobati kanthi efektif karo penisilin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum nyebabake sifilis liwat kontak seksual utawa saka ibu marang bayi nalika meteng. Sanajan ana tes sing gampang kanggo diagnosa lan perawatan kanthi siji suntikan penisilin sing dawa tumindak kanthi apik, sifilis dadi masalah gedhe maneh ing saindenging jagad. Iki luwih bener ing antarane wong lanang sing duwe jinis karo wong lanang (MSM) ing negara kanthi penghasilan dhuwur lan menengah. Nalika sawetara negara berpendapatan rendah wis nggayuh tujuan WHO kanggo mungkasi sifilis saka ibu menyang bayi, ana peningkatan sifilis ing antarane MSM sing positif HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Enlarged Ati: Iki asring ditemokake lan bisa kedadeyan bebarengan karo limpa sing luwih gedhe. Priksa biopsi ati ing mikroskop darkfield bisa nuduhake anané spirochete. Tes fungsi ati bisa nuduhake kelainan. (2) Kulit Kuning (Jaundice) : Apa ana wong sing nuduhake jaundice gumantung saka jumlah ati sing kena pengaruh. (3) Runny Nose: Asring salah siji saka tandha pisanan, biasane ing minggu pisanan sawise lair. (4) Kelenjar Limfa Abuh: Pembengkakan umum kelenjar getah bening, biasane ora krasa lara, uga umum. (5) Rash Kulit: Ruam biasane katon siji nganti rong minggu sawise irung meler. Sampeyan bisa uga ndeleng bintik abang utawa jambon cilik ing mburi, bokong, pupu, lan tlapak sikil. Ruam iki bisa berkembang dadi peeling lan crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Diagnosis lan Perawatan
VDRL lan RPR bisa digunakake kanggo konfirmasi infèksi anyar lan layar kanggo syphilis. Tes FTA-ABS minangka tes sing luwih spesifik lan bisa digunakake kanggo mriksa riwayat infeksi sadurunge. Penisilin digunakake kanggo nambani sifilis.