Urticaria pigmentosa - Urtikaria Pigmentosa
Urtikaria Pigmentosa (Urticaria pigmentosa) minangka wangun mastositosis kulit sing paling umum. Iki minangka penyakit langka sing disebabake dening jumlah sel mast sing akeh banget ing kulit sing nyebabake gatal-gatal utawa lesi ing kulit nalika iritasi. Titik abang utawa coklat asring katon ing kulit, biasane ing dhadha, bathuk, lan mburi. Sel mast iki, nalika iritasi (contone, kanthi nggosok kulit, paparan panas), ngasilake histamin sing akeh banget, nyebabake reaksi alergi sing nyebabake gatal-gatal sing dilokalisasi ing area iritasi, kadhangkala disebut "Tanda Darier".
☆ Ing asil Stiftung Warentest 2022 saka Jerman, kepuasan konsumen karo ModelDerm mung luwih murah tinimbang konsultasi telemedicine sing dibayar.
References
Mastocytosis minangka kondisi ing ngendi ana keluwihan sel mast, asring ditemokake ing macem-macem bagian awak kaya kulit, sumsum balung, lan sistem pencernaan. Miturut Organisasi Kesehatan Dunia (WHO) , cutaneous mastocytosis bisa digolongake dadi telung jinis utama. Jinis pisanan (mastocytomas) kasusun saka lesi tunggal utawa sawetara (≤3) . Jinis kapindho (urticaria pigmentosa) nglibatake pirang-pirang lesi, biasane saka luwih saka 10 nganti kurang saka 100. Tipe pungkasan nuduhake keterlibatan sing nyebar ing kulit. Urticaria pigmentosa minangka wangun mastositosis kulit sing paling umum ing bocah-bocah, nanging bisa uga ana ing wong diwasa. Biasane kondisi sing ora mbebayani sing asring saya apik nalika remaja. Ora kaya mastositosis wong diwasa, urticaria pigmentosa arang banget mengaruhi organ internal. Salah sawijining ciri khas urticaria pigmentosa yaiku cenderung nyebabake bintik-bintik cilik, gatal, coklat-abang, utawa coklat-kuning ing kulit, sing umum dikenal minangka hives. Bintik-bintik iki biasane katon nalika isih cilik lan bisa tahan ing saindhenging urip.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Bocah wadon umur 6 taun teka kanthi pirang-pirang bintik warna peteng sing pisanan katon ing kulit sirah lan banjur nyebar menyang rai lan awak sajrone nem wulan kepungkur. Dheweke ujar manawa dheweke mundhak, dadi abang, lan gatal nalika ditrapake. Dheweke ora ngalami flushing, muntah, diare, utawa wheezing, lan riwayat medis pribadi lan kulawarga ora menehi pitunjuk sing relevan. Sawise dipriksa, kita nemokake pirang-pirang bintik peteng ing kulit sirah, bathuk, rai, lan gulu, bebarengan karo bintik-bintik peteng sing rada mundhak ing dhadha lan punggung. Digosok kanthi entheng bintik-bintik kasebut nyebabake bengkak lan gatal sajrone 2 menit, nanging gejala kasebut ilang sajrone 15-20 menit (Darier's sign) .
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
