ព័ត៌មាន​បន្ថែម ― Khmer

Pigmented purpuric dermatoses (PPD) គឺជាក្រុមនៃជំងឺស្បែកដែលត្រូវបានកើតឡើងដោយតំបន់តូចៗនៃការហូរឈាមក្រោមស្បែកដោយសារតែការរលាក capillaritis។ PPD ជាអាការៈចាប់ផ្តើមជាចំណុចក្រហមទៅពណ៌ស្វាយ ដែលក្រោយមកប្រែទៅជាពណ៌មាស‑ត្នោត នៅពេលដែល hemosiderin ត្រូវបានស្រោបយកឡើងវិញ។
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.

Schamberg disease គឺជាប្រភេទទូទៅបំផុតនៃ pigmented purpuric dermatoses (PPDs) ដែលជាជំងឺស្បែករ៉ាំរ៉ៃដែលសម្គាល់ដោយចំណុចក្រហម ឬពណ៌ស្វាយតូចៗ និងពណ៌ស្បែកកើនឡើង (បំណះពណ៌ត្នោត ក្រហម ឬលឿង) ។ PPDs ត្រូវបានចាត់ថ្នាក់ជាប្រាំប្រភេទ៖ Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, eczematoid-like purpura of Doucas and Kapetanakis ។ Schamberg disease (SD) ត្រូវបានគេស្គាល់ថាជា progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, Schamberg's purpura ។ វាប៉ះពាល់ដល់បុរសជាចម្បង ហើយជាធម្មតាលេចឡើងនៅលើជើងខាងក្រោម ប៉ុន្តែក៏អាចកើតមាននៅលើភ្លៅ គូទ ប្រម៉ោយ ឬដៃផងដែរ។
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.

ព័ត៌មានស្តីពីអ្នកជំងឺ 113 នាក់ដែលមាន PPD ត្រូវបានវិភាគ, ក្នុងនោះមាន 38 នាក់ដែលបានធ្វើកាវីស្បែកសម្រាប់ការសិក្សានេះ។ ប្រភេទគ្លីនិកដែលพบบ่อยที่สุดគឺជំងឺ Schamberg (60.5%)។ ជំងឺផ្សេងទៀតที่เกี่ยวข้องรวมถึงជំងឺសំពាធឈាម (hypertension) (15.8%) និងជំងឺទឹកនោមផ្អែម (diabetes) (10.5%) និងอื่นៗ។ ប្រវត្តិថ្នាំដែលបានប្រើรวมถึง statins (13.2%), beta blockers (10.5%) និងอื่นៗ។ ปัจจัยที่อาจเกี่ยวข้องรวมถึงการติดเชื้อทางเดินหายใจส่วนบน (upper respiratory infection) (5.3%), ความดันออร์โธสแตติกสูงจากการยืนนาน (orthostatic pressure) (2.6%) และการออกกำลังกายหนัก (strenuous exercise) (2.6%)។ การรักษาได้ครอบคลุมผู้ป่วย 36 នាក់ (94.7%) ด้วยวิธีการหนึ่งหรือหลายวิธี ได้แก่ oral antihistamines, pentoxifylline, topical steroids, และ/หรือ phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.