Staphylococcal scalded skin syndrome
☆ នៅក្នុងលទ្ធផល Stiftung Warentest ឆ្នាំ 2022 ពីប្រទេសអាឡឺម៉ង់ ការពេញចិត្តរបស់អ្នកប្រើប្រាស់ជាមួយ ModelDerm គឺទាបជាងការពិគ្រោះថ្លៃព្យាបាលតាមទូរស័ព្ទបន្តិចប៉ុណ្ណោះ។
ទារកដែលមាន Staphylococcal scalded skin syndrome
References
Staphylococcal Scalded Skin Syndrome គឺជាស្ថានភាពដែលស្បែកស្រក់ដោយសារជាតិពុលដែលផលិតដោយបាក់តេរី Staphylococcus មួយចំនួន។ វាជារឿងចម្លែកចំពោះក្មេងអាយុលើសពី ៦ ឆ្នាំ។ វាក៏អាចកើតឡើងចំពោះមនុស្សពេញវ័យដែលមានប្រព័ន្ធការពាររាងកាយចុះខ្សោយ ឬបញ្ហាតម្រងនោមធ្ងន់ធ្ងរ។ លក្ខណៈពិសេសចម្បងគឺការរបកស្បែកយ៉ាងទូលំទូលាយបន្ទាប់ពីការរលាក។ ភាពធ្ងន់ធ្ងរមានចាប់ពីពងបែកមួយចំនួន រហូតដល់ការបាត់បង់ស្បែកដែលរីករាលដាល ដែលអាចបណ្តាលឱ្យមានការធ្លាក់ចុះយ៉ាងខ្លាំងនៃសីតុណ្ហភាពរាងកាយ និងអស្ថេរភាពនៃសម្ពាធឈាម។
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
ក្មេងប្រុសអាយុ១០ខែម្នាក់ហៀរសំបោរ ញ៉ាំមិនបានស្រួល។ គ្រូពេទ្យបាននិយាយថា វាជាការឆ្លងមេរោគផ្លូវដង្ហើមខាងលើ។ ពីរថ្ងៃក្រោយមក គាត់បានត្រលប់មកវិញ ដោយសារតែគាត់មិនធូរស្បើយ និងមានបញ្ហាថ្មីៗ ដូចជាមុខហើម និងស្បែករលាកជុំវិញមាត់។ ក្នុងរយៈពេលពីរថ្ងៃបន្ទាប់ ក្មេងប្រុសនោះកាន់តែអាក្រក់ទៅៗ។ ដៃនិងជើងរបស់គាត់បានហើមឡើង ហើយស្បែករបស់គាត់បានចាប់ផ្តើមចេញ។ ត្រឡប់មកមន្ទីរពេទ្យវិញ គ្រូពេទ្យបានកត់សម្គាល់ឃើញមានកន្ទួលក្រហមនៅលើមុខ និងផ្នត់នៃស្បែករបស់គាត់ ដែលរលាកនៅពេលប៉ះ។ ពួកគេបានធ្វើរោគវិនិច្ឆ័យគាត់ថាមាន staphylococcal scalded skin syndrome (SSSS) ហើយចាប់ផ្តើមគាត់ប្រើថ្នាំអង់ទីប៊ីយោទិចតាមសរសៃឈាមវ៉ែន។
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
ក្មេងស្រីអាយុ 2 ឆ្នាំម្នាក់បានលេចចេញនូវកន្ទួលពេញរាងកាយរបស់នាងដែលបានវិវត្តជាង 48 ម៉ោង បន្ទាប់ពីសត្វល្អិតខាំនៅលើមុខរបស់នាងកាលពីថ្ងៃមុន។ ក្នុងអំឡុងពេលពិនិត្យ នាងបានឡើងកន្ទួលរមាស់ជាដុំៗដែលផ្សំឡើងពីដុំតូចៗ ហើយនៅពេលដែលលាបស្រាលៗ ស្បែករបស់នាងបានបង្ហាញពីសញ្ញារបស់ Nikolsky។ មិនមានសញ្ញានៃកន្ទួលដែលប៉ះពាល់ដល់ភ្នាសរំអិលរបស់នាងទេ។ ការធ្វើតេស្តលើឈាមរបស់នាងមិនបានបង្ហាញសញ្ញាណាមួយនៃការឆ្លងនោះទេ។
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
រោគសញ្ញានេះត្រូវបានបង្កឡើងដោយ epidermolytic exotoxins (exfoliatin) A និង B ដែលត្រូវបានបញ្ចេញដោយ S. aureus ។ ការព្យាករណ៍នៃ staphylococcal scalded skin syndrome ចំពោះកុមារគឺល្អឥតខ្ចោះ ជាមួយនឹងដំណោះស្រាយពេញលេញក្នុងរយៈពេល 10 ថ្ងៃនៃការព្យាបាល និងដោយគ្មានស្លាកស្នាមគួរឱ្យកត់សម្គាល់។ ទោះជាយ៉ាងណាក៏ដោយ staphylococcal scalded skin syndrome ត្រូវតែត្រូវបានបែងចែកយ៉ាងប្រុងប្រយ័ត្នពីជាតិពុល epidermal necrolysis ដែលនាំឱ្យមានការព្យាករណ៍មិនល្អ។
○ ការធ្វើរោគវិនិច្ឆ័យ និងការព្យាបាល
ការធ្វើរោគវិនិច្ឆ័យខុសថាជាដំបៅត្រអកដូចជាជំងឺរលាកស្បែក atopic dermatitis និងការប្រើថ្នាំស្តេរ៉ូអ៊ីតធ្វើឱ្យដំបៅកាន់តែធ្ងន់ធ្ងរ។ សូមស្វែងរកការព្យាបាលឱ្យបានឆាប់តាមដែលអាចធ្វើទៅបាន ខណៈពេលកំពុងលាបថ្នាំអង់ទីប៊ីយោទិច។
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#First-generation cephalosporins (e.g. Cefradine)
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