Acanthosis nigricans - 흑색극세포증
비만한 사람에게 흔히 발생합니다.
References
Acanthosis nigricans 은 기저 질환의 피부 증상입니다. 목, 겨드랑이, 사타구니 등 피부가 접히는 부위에 흔히 나타나며, 가장자리가 불분명한 벨벳처럼 어두운 반점처럼 보입니다. 이 상태는 일반적으로 당뇨병 및 인슐린 저항성과 관련이 있지만 드물게 신체 내부의 암을 나타낼 수도 있습니다. 호르몬 문제나 스테로이드, 피임약과 같은 특정 약물 복용으로 인해 나타날 수도 있습니다.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) 은 인슐린 저항성, 당뇨병, 비만, 특정 암, 호르몬 문제 및 약물 반응과 같은 다양한 건강 문제와 관련된 일반적인 피부 상태입니다. AN 치료는 근본적인 건강 문제를 해결하는 데 중점을 둡니다. 처음에 의사는 비만, 고콜레스테롤, 고혈압, 제2형 당뇨병을 포함하는 인슐린 저항성 증후군의 징후가 있는지 확인합니다. 의사들은 피부가 두꺼워지는 데 도움이 될 수 있는 첫 번째 치료법으로 topical retinoids 을 처방하는 경우가 많습니다. 그러나 피부가 어두워지는 현상을 완전히 해결하지 못할 수도 있습니다. Salicylic acid, podophyllin, urea, and calcipotriol 과 같은 다른 치료 옵션도 자주 적용해야 합니다.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ 원인
이는 일반적으로 40세 미만의 개인에게 발생하며 유전적으로 유전될 수 있으며 비만이나 갑상선 기능 저하증, 말단 비대증, 다낭성 난소 질환, 인슐린 저항성 당뇨병 또는 쿠싱병과 같은 내분비 질환과 관련이 있습니다.
○ 치료 ― OTC 의약품
#40% urea cream