Livedoid vasculitis - 청피반성 혈관염https://en.wikipedia.org/wiki/Livedoid_vasculitis
청피반성 혈관염 (Livedoid vasculitis) 은 청년~중년 여성에게 주로 나타나는 만성 피부질환이다. 그 특징을 설명하는 데 사용되는 약어 중 하나는 "하지의 망상 패턴을 갖는 통증성 자색궤양"(보라색)입니다. 이는 만성 정맥 고혈압 및 정맥류를 포함한 여러 질병과 관련이 있습니다.

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    References Livedoid vasculopathy: A review with focus on terminology and pathogenesis 36285834 
    NIH
    Livedoid vasculopathy 은 다리 아래쪽에 계속해서 통증이 나타나는 궤양이 나타나는 희귀한 피부 질환입니다.
    Livedoid vasculopathy (LV) is a rare thrombotic vasculopathy of the dermis characterized by painful, relapsing ulcers over the lower extremities. Diagnosis is challenging due to the overlap in clinical appearance and nomenclature with other skin disorders. Treatment selection is complicated by poor understanding of the pathogenesis of LV and lack of robust clinical trials evaluating therapy efficacy. The terminology and pathophysiology of LV are reviewed here, along with its epidemiology, clinical and histologic features, and treatment options. A diagnostic pathway is suggested to guide providers in evaluating for comorbidities, referring to appropriate specialists, and choosing from the available classes of therapy.
     Livedoid vasculopathy: A review of pathogenesis and principles of management 27297279
    Livedoid vasculopathy 은 다리 아래쪽에 재발성 궤양을 유발하고 위축성 블랜치로 알려진 창백한 흉터를 남기는 희귀한 피부 질환입니다. 정확한 원인은 아직 불분명하지만, 혈액 응고 증가 (hypercoagulability) 가 주요 요인이고 염증이 부차적인 역할을 하는 것으로 여겨집니다. 응고에 기여하는 요인은 다음과 같습니다 - deficiencies in proteins C and S, genetic mutations like factor V Leiden, antithrombin III deficiency, prothrombin gene mutations, high levels of homocysteine. 생검에서 이 상태는 혈관 내부의 혈전, 혈관벽의 두꺼워짐, 흉터를 보여줍니다. 치료에는 항혈소판제, 혈액 희석제, 섬유소 용해 요법과 같은 약물을 사용하여 혈전을 예방하는 데 초점을 맞춘 다각적인 접근 방식이 포함됩니다. 이 피부 상태에는 다양한 약물을 사용할 수 있습니다 - colchicine and hydroxychloroquine, vasodilators, immunosuppressants.
    Livedoid vasculopathy is a rare skin condition that causes recurring ulcers on the lower legs, leaving behind pale scars known as atrophie blanche. While the exact cause is still unclear, it's believed that increased blood clotting (hypercoagulability) is the main factor, with inflammation playing a secondary role. Factors contributing to clotting include as follows - deficiencies in proteins C and S, genetic mutations like factor V Leiden, antithrombin III deficiency, prothrombin gene mutations, high levels of homocysteine. In biopsies, the condition shows blood clots inside vessels, thickening of vessel walls, and scarring. Treatment involves a multi-pronged approach focusing on preventing blood clots with medications like anti-platelet drugs, blood thinners, and fibrinolytic therapy. Various drugs can be used for this skin condition - colchicine and hydroxychloroquine, vasodilators, immunosuppressants.
     Livedoid Vasculopathy 32644463 
    NIH
    Livedoid vasculopathy 은 양쪽 다리에 병변이 나타나는 드문 질환입니다. 작은 혈관에 혈전이 형성되는 것은 혈관 내벽의 손상과 함께 응고가 증가하고 혈전 분해가 감소하여 발생하는 것으로 생각됩니다. 이는 여성, 특히 15~50세 사이에서 더 흔합니다. 금연, 상처 관리, 혈액 희석제 및 항혈소판제와 같은 약물 사용이 효과적이었습니다.
    Livedoid vasculopathy is a rare vasculopathy that is typically characterized by bilateral lower limb lesions. Increased thrombotic activity and decreased fibrinolytic activity along with endothelial damage are believed to be the cause of thrombus formation in the capillary vasculature. It is 3 times more common in females than in males, especially in patients between the ages of 15 to 50 years. There is no definite first-line treatment, but general measures like smoking cessation, wound care, and pharmacological measures like anticoagulants and antiplatelets have shown good results.