Melasma - 기미
40대 초반 아시아 여성에게서 흔히 나타나는 증상이다. 사진 속 동그라미 부분은 기미보다는 흑색점에 가깝습니다.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
최근 low-fluence Q-switched Nd:YAG (LFQSNY) 레이저는 특히 아시아 지역에서 기미 치료에 인기를 얻고 있습니다. 다양한 연구를 요약하는 것이 어려웠지만 LFQSNY는 기존 치료법에 비해 일반적으로 기미에 효과적이고 안전한 것으로 보입니다. 그러나 일부 얼룩덜룩한 색소침착 저하 사례가 LFQSNY의 부작용으로 보고되었는데, 이는 아마도 높은 레이저 에너지로 인한 것일 수 있습니다. LFQSNY를 적극적으로 사용하면 특히 어두운 피부색에서 염증으로 인한 과다 색소 침착이 발생할 수 있습니다.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
색소침착 문제는 일차 진료에서 종종 발견됩니다. 과다색소침착 장애의 일반적인 유형에는 post-inflammatory hyperpigmentation, melasma, sunspots, freckles, and café au lait spots 이 포함됩니다.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
기미는 색소가 지속적으로 생성되는 질환이기 때문에 일정기간 레이저 치료로 해결될 수 없습니다. Tranxenemic acid는 색소 침착을 개선하는데 도움을 줍니다.
○ 치료
일부 국가(예: 일본, 한국)에서는 경구용 트라넥삼산을 일반의약품으로 구입할 수 있으며 효과적입니다. 트라넥삼산과 아젤라산이 함유된 기미 크림이 부분적으로 도움이 될 수 있습니다.
하이드로퀴논은 과다색소침착 치료를 위해 국소적으로 사용될 수 있지만 FDA는 2020년부터 하이드로퀴논을 함유한 OTC 제품을 중단했습니다.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma