Acanthosis nigricans
☆ Di encamên 2022-an de Stiftung Warentest ji Almanyayê, razîbûna xerîdar bi ModelDerm tenê ji şêwirmendên telemedicine drav hindik hindiktir bû.
Di mirovên qelew de gelemperî ye.
relevance score : -100.0%
ReferencesAcanthosis nigricans diyarîyek çermî ya bingehîn e. Ew bi gelemperî di pelên çermê yên mîna stû, mil û gewr de xuya dike, wek lekeyên tarî yên qedifî bi rêze nezelal. Ev rewş bi gelemperî bi şeker û berxwedana însulînê ve girêdayî ye, lê di rewşên kêm de dikare nîşana kansera hundurê laşê bide. Hêdî‑hêdî jî dibe ku ji ber pirsgirêkên hormonî an ji ber bikaranîna dermanên taybetî yên wek steroîd û kontrola zayînê xuya bibe.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) rewşek çermê hevpar e ku bi pirsgirêkên tenduristiyê yên cihêreng, mîna berxwedana însulînê, şeker, qelewbûn, hin penceşêrê, pirsgirêkên hormonal, û reaksiyonên li ser dermanan ve girêdayî ye. Dermankirina AN li ser çareserkirina pirsgirêkên bingehîn ên tenduristiyê dike. Di destpêkê de, bijîjk nîşanên sendroma berxwedana însulînê, ku tê de qelewbûn, kolesterolê bilind, tansiyona xwînê ya bilind, û şekerê 2‑type hene, kontrol dike. Bijîjk bi gelemperî topical retinoids wekî bijareya dermankirinê ya yekem destnîşan dike, ku dikare di stûrbûna çerm de alîkar be. Lêbelê, ev dikarin bi tevahî tarîbûna çerm çareser nekin. Vebijarkên din ên dermankirinê (salicylic acid, podophyllin, urea, calcipotriol) jî hewceyê serîlêdana pir caran ne.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ Causes
Ew bi gelemperî di mirovên ji 40 salî piçûk tê de çêdibe, dibe ku ji hêla genetîkî ve were mîras kirin û bi qelewbûn an endokrînopatiyên mîna hîpotyroidîzm, akromegalî, nexweşiya polycystic, şekerê (insulîn‑berxwedêr) an nexweşiya Cushing ve girêdayî ye.
○ Dermankirin - Dermanên OTC
#40% urea cream