Angiofibroma
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ReferencesCutaneous angiofibromas dikarin li gelek deverên laşê xuya bibin. Li ser rû, ev bi gelemperî wekî papulên fibrous an adenoma sebaceum têne zanîn; li ser penîsê, wan bi navê pearly penile papules tê gotin; di bin neynûkê de, wan bi navê angiofibromas periungual an tîmorên Koenen têne nasîn; û li devê, ev wekî fibroma devkî têne binav kirin. Angiofibromasên rû taybetmendiyek berbiçav a tuberous sclerosis (TS) in, nexweşiyek mîrasî ku bandorê li çerm, gurçik, dil, mêjî û pişikê dike. Ew bi gelemperî di dema zaroktiyê an destpêka mezinbûnê de li ser rûyê mirovên bi TS pêşve diçin. Hebûna sê an zêdetir angiofibromasên rû an du an jî zêdetir angiofibromasên periungual di teşhîskirina TS de girîng tê hesibandin. Wekî din, dibe ku di şert û mercên (multiple endocrine neoplasia type 1 (MEN-1) û Birt-Hogg-Dubé syndrome) de gelek angiofibroma rûyê hebin. Pearly penile papules li kêleka koronal û şûşa penîsê têne dîtin. Ew pêlên domdar, bê êş in, ku bi gelemperî di nav mêrên sinetnebûyî de têne dîtin.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) Rû – Fibrous papule
2) Penîs – Pearly penile papule
3) Di bin neynûka tiliyê yan li ser pê de – Periungual angiofibroma