Intraepithelial carcinoma (Bowen disease) - Kansera Intraepithelial (Nexweşiya Bowen)
☆ Di encamên 2022-an de Stiftung Warentest ji Almanyayê, razîbûna xerîdar bi ModelDerm tenê ji şêwirmendên telemedicine drav hindik hindiktir bû.
Bûyera tîpîk ― Kansera Intraepithelial (Nexweşiya Bowen) (Intraepithelial carcinoma (Bowen disease)) dibe ku wekî eczemayek dirêj-mayînde, ne-xurşî bi xeletî were teşhîs kirin.
References
Bowen's disease (BD) cureyek penceşêra çerm e ku di tebeqeya derve ya çerm (epidermis) de dest pê dike. Ew di Kafkasiyan de pirtir e û pir caran li deverên ku di bin tîrêja rojê de ne pêk tê, lê ew dikare li cîhek din jî xuya bibe. BD bi gelemperî wekî birînek yekane xuya dike. BD bi gelemperî wekî nîşanek hişyariyê tê dîtin berî ku celebek ciddî ya kansera çerm pêşve bibe. Ji bo teşhîskirina BD, bijîjk bi gelemperî li ser vekolîna nimûneyên tevnê di binê mîkroskopê de (biopsî) ve girêdayî ne.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease bi piranî bandorê li kesên spî yên ji 60 salî mezintir dike. Faktorên xetereyê yên sereke girtina tavê ya demdirêj, qelsbûna pergala parastinê, rûdana arsenîk, û enfeksiyona HPV ya çerm in. Stranên HPV 16, 18, 34, û 48 bi nexweşiya Bowen re li deverên genîtal ve girêdayî ne. Tevlêbûna HPV di rewşên ne-genital de kêmtir eşkere ye.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bi gelemperî li her deverek laş wekî deverek erythematous, qermîçok an qerisî xuya dike. Cihê herî gelemperî lingên jêrîn e.
Ew bi vebijarkên cûrbecûr yên dermankirinê yên wekî kryoterapî, curettage, cautery, terapiya fotodînamîkî, an derxistina birînê tê derman kirin.
○ Nîşanî û dermankirin
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy