Agahiyên bêtir ― Kurdî (kurmancî)

Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.

Panniculitis komeke heterojen a nexweşiyên înflamatuar ên ku tevna rûnê ya binê çerm vedihewîne pêk tîne. Ev nexweşî di zarokan de kêm in. Panniculitis dikare bibe pêvajoya bingehîn di nexweşiyek pergalî an pêvajoyek duyemîn de ku ji enfeksiyon, trawma an vegirtina dermanan pêk tê. Piraniya celebên panniculitis xwedan heman pêşandana klînîkî ne (bêyî etiolojiyê) , bi girêkên binerdê yên nerm, erythematoz.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.

Panniculitis , iltîhaba rûnê binê çerm, bi gelemperî bi girêkên înflamatuar re xuya dike. Erythema nodosum (EN) ji hêla klînîkî ve forma herî gelemperî ya panniculitis e. Digel ku ji% 55-ê EN-ê îdiopathîk tê hesibandin, sedemên herî gelemperî enfeksiyon, derman, nexweşiyên pergalî yên wekî sarcoidosis û nexweşiya înflamatuar a rovî, ducanî, û nebaşiyê ne. EN bi gelemperî di ciwan û 20-an de diyar dibe, û bi gelemperî di jinan de tê dîtin. Ew pir caran bi prodromeyek ne-taybetî ya yek-sê hefte tê pêş, ku dibe ku germ, nexweşî, û nîşanên enfeksiyonek rêça respirasyonê ya jorîn jî hebe. Dûv re birînên çermî têne peyda kirin, ku bi gelemperî li ser aliyên dirêjkirî yên lingan têne cih kirin. Birînên girover an ovalî bi êş in, piçekî bilindkirî ne, girêkên sor ên ne ulceratîf in. Patogeneza tam a EN nayê fêm kirin, her çend tê texmîn kirin ku ji depokirina kompleksên xweparastinê yên di venûlên septayê de di rûnê binê çerm de, dibe sedema pannikulîtek neutrofîlî. Tewra bêyî dermankirina taybetî ya ji bo rewşek sedemî, EN di pir rewşan de bêyî dermankirinê çareser dibe.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.