Prurigo nodularis
☆ Di encamên 2022-an de Stiftung Warentest ji Almanyayê, razîbûna xerîdar bi ModelDerm tenê ji şêwirmendên telemedicine drav hindik hindiktir bû.
References
Prurigo nodularis rewşek çermê dirêj-mayînde ye ku bi gelek pêlên hişk û girêk, bi gelemperî li perçeyên derveyî dest û lingan têne dîtin. Rengê van kulm dikarin ji rengê goşt heya pembe cûda bibin û pir bi xiş in. Ew dikarin li ser mirovên her temenî bandor bikin û bi gelemperî bi şert û mercên çerm ên din ên ku dibin sedema xişiya kronîk, mîna dermatitis atopîk ve girêdayî ne. Vebijarkên dermankirinê dermanên xurt ên li dijî xişê, dermanên ku bandorê li pergala berevaniyê dikin, û dermanên ku pergala nervê dikin hedef hene. Birêvebirina prurigo nodularis bi gelemperî terapiya demdirêj pêk tîne.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Dermankirin bi gelemperî bi karanîna kreman an derziyên steroîdan li ser devera bandorkirî pêk tê. Di rewşên girantir an serhişk de, dibe ku dermankirinên mîna tedawiya sivik an dermanên ku pergala berevaniyê tepeser dikin hewce bibin. Thalidomide û lenalidomide ji bo rewşên giran vebijark in, lê ew dikarin bandorên alîgir ên cidî hebin. Dermanên nûtir (opioid receptor antagonists, neurokinin-1 receptor antagonists) di dermankirina prurigo nodularis de bi kêm bandorên alîgir re li gorî thalidomide an lenalidomide soz dide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Chronic prurigo rewşek çerm e ku bi xişbûna demdirêj (ji 6 hefteyan re dom dike) , birînên çerm ên girêdayî xişandinê, û dîrokek pir caran xişandinê tête diyar kirin. Ew di çerm de neuroinflammasyon û fibrosisê vedigire.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Prurigo nodularis pirsgirêkek çermê ya dirêj-mayînde ye ku bi girêkên xurandinê ve tê destnîşan kirin. Em tam nizanin ka sedema wê çi ye, lê wusa dixuye ku pirsgirêkên berevanî û nervê di çerxa xiş-xurkirinê de rolek dileyzin. Heya nuha, ti dermankirinek ku ji hêla FDA ya Dewletên Yekbûyî ve bi taybetî ji bo prurigo nodularis hatî pejirandin tune.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
○ Dermankirin - Dermanên OTC
Şuştina cihê birînê bi sabûnê qet alîkarî nake û dikare wê xirabtir bike. Dibe ku rûnên steroîdên OTC bibin alîkar ku nîşanan sist bikin, lê bi gelemperî hewce ne ku ew çend hefte werin sepandin da ku çêtir bibin. Berdewamkirina girtina antîhîstamînan jî dibe alîkar ku xişiyê sist bike.
#OTC steroid ointment
#OTC antihistamine
○ Demankirinî
#Intralesional triamcinolone injection