Syphilis - Sifîlîs
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Chancres - enfeksiyona sifilîtîk ya bingehîn ji hêla Treponema pallidum ve
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ReferencesSifilîs nexweşiyek e ku ji aliyê zayendî ve tê, ji bakteriya Treponema pallidum ve çê dibe. Di vê lêkolînê de, em li ser 57 nexweşên di navbera 18 û 68 salî de, yên ku sifilîsa duyemîn hene, balê dikin.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Sifîlis enfeksiyonek bakterî ye ku ji hêla Treponema pallidum ve çêdibe. Ew dikare nexweşiyên cûrbecûr teqlîd bike û paşnavê “great imitator” jê re bibe. Sifîlis hîn jî li seranserê cîhanê bi mîlyonan kesan bandor dike, lê dikare bi penîsîlînê bi bandor were derman kirin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum di dema ducanîyê de bi têkiliya zayendî an jî ji dayikê bi zarok re dibe sedema sifilisê. Her çend ceribandinên hêsan hebin, ji bo teşhîskirina wê û dermankirina bi yek şûşeyek penîsîlînê ya demdîrêj baş dixebite, sifilis li seranserê cîhanê dîsa pirsgirêkek mezin dibe. Ev yek bi taybetî di nav mêrên ku li welatên xwedî dahatên bilind û navîn bi mêran re (MSM) re seks dikin, rast e. Digel ku hin welatên kêm-dahat armancên WHO ji bo rawestandina derbasbûna sifilisê ji dayikê bo pitik bigihîjin, lê di nav MSM-ya HIV-pozîtîf de zêdebûna metirsîdar a sifilisê heye.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Kezeba mezinbûyî: Ev gelemperî tê dîtin û dibe ku li kêleka zikê mezinbûyî çêbibe. Biopsiya kezebê di bin mikroskopê qada tarî de dibe ku hebûna spirochete nîşan bide. Testên fonksiyona kezebê jî dikarin anormaliyan nîşan bidin. (2) Zerbûna Çermê (Zerk): Ger kesek zerikê nîşan bide, ev diyar dike ku kezeba çiqasî bandor dike. (3) Pozê diherike: Ev gelemperî yek ji nîşanên yekem e, ku di hefteya yekem a piştî zayînê de xuya dibe. (4) Germên lîmfê yên werimî: Werimîna giştî ya girêkên lenfê, ku bi gelemperî bê êş e, jî gelemperî tê dîtin. (5) Reşîka Çermê: Pişkek bi gelemperî di nav yek‑du hefteyan de piştî rijandina pozê xuya dibe. Hûn dikarin li ser pişt, qûn, ran û lingên lingan deqên piçûk ên sor an pembe bibînin. Ev rijandîn dikare berî pehîn û pelçiqandinê pêşve bibe.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Nîşanî û dermankirin
VDRL û RPR dikarin were bikar anîn da ku enfeksiyona dawîn piştrast bikin û ji bo sifîlîsê nîşan bide. Testa FTA-ABS ceribandinek taybettir e û dikare were bikar anîn da ku dîroka enfeksiyonê ya berê kontrol bike. Penicillin ji bo dermankirina sifîlîsê tê bikar anîn.