Acute generalized exanthematous pustulosishttps://en.wikipedia.org/wiki/Acute_generalized_exanthematous_pustulosis
☆ In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis. Late laesiones cum erythemate et pusulis repente apparent.
Erythema et pusulae sine pruritu subito fiunt.
relevance score : -100.0%
References Acute Generalized Exanthematous Pustulosis 37276304 NIH
Acute generalized exanthematous pustulosis (AGEP) Est reactionis pelliculae parvis, pus repletis labefecit in basi cutis rubra. Solet autem fieri, cum medicamenta quaedam sumunt, ut antibiotica, celeriterque per corpus diffunditur. Cum medicamento excitato reprimendo, signa typice intra duas septimanas abeunt, saepe aliqua cutis effusio relinquens. Etsi plerumque non sunt graves et ad cutem restrictae, causae graves possunt latere cum aliis reactionibus gravibus cutis sicut Stevens-Johnson syndrome vel toxic epidermal necrolysis. Curatio principaliter cura adminicula est, et deploratio pro perfecto resolutione morbi praestans plerumque est.
Acute generalized exanthematous pustulosis (AGEP) is an adverse cutaneous reaction characterized by sterile pinpoint nonfollicular pustules atop an erythematous background. Symptoms most often occur in the setting of medication exposure, such as systemic antibiotics, rapidly become generalized, followed by desquamation and resolution within about two weeks of discontinuing the offending trigger. Although mostly self-limited without systemic involvement, severe cases are classified alongside other cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Treatment is primarily supportive, and the prognosis for complete resolution is excellent.
Acute Generalized Exanthematous Pustulosis: Clinical Characteristics, Pathogenesis, and Management 36702114Recent experimental data reviewed herein are supportive of an early role of drug-induced innate immune activation and innate cytokines such as interleukin (IL)-1, IL-36, and IL-17 in the pathogenesis of AGEP. This explains the rapid onset and neutrophilic character of the cutaneous inflammation.
Acute Generalized Exanthematous Pustulosis - Case report 36876416 NIH
Vir LXXVI annos natus ad tempus cubiculi venit quod pellis eius praeterito biduo mutaverat. Doctores inaequaliter rubra invenerunt et areas in stipite et brachiis et cruribus excitaverunt. Procedente tempore, hae inaequaliter conjunctae sunt, et pustulis sicut labefecit in locis rubris. Testi ostendit cellam sanguineam albam summam cum sortibus typum appellatum neutrophils, et gradus C-reactive protein auctus est.
A 76-year-old male patient presented as an emergency due to a 2-day history of skin changes. Physical examination revealed disseminated erythematous macules and plaques on the trunk and extremities. In the further course, confluence of the macules and non-follicular pustulosis developed in the area of erythema. Laboratory tests revealed leukocytosis with neutrophils and elevated C-reactive protein.