Angiofibroma Papula dura, nodulus, vel laesiones tumorales. Angiofibromae interdum misdiagnoscuntur ut acne. Apparent in locis suis: I) in facie – Papula fibrosa (Fibrous papule) II) in penis – Papula penialis perlata (Pearly penile papule) III) sub unguis vel ungula – Angiofibroma periungualis (Periungual angiofibroma)
Angiofibromas are small, reddish brown or even flesh-colored, smooth, shiny, 0.1 to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks. They contain fibrous tissue.
☆ AI Dermatology — Free Service In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
Angiofibroma speciem acne similem habet. Vitia maxime circa nares occurrunt.
Cutaneae angiofibromas in variis corporis partibus apparere possunt. In facie saepe notae sunt papulae fibrosae vel adenoma sebaceum; in penis,' dicuntur pearly penile papules; sub ungue, angiofibromas seu tumores periunguales nominantur; et in ore ad fibromata oralia referuntur. Angiofibromas faciei, quae notae sunt tuberous sclerosis (TS), sunt inordinatio hereditaria quae cutem, renes, cor, cerebrum et pulmones afficit. Saepe apparent in facie in pueritia vel iuventute apud singulos cum TS. Habentes tres vel plures angiofibromas faciales vel duos vel plures angiofibromas periunguales significantes, considerantur diagnosticum TS. Accedit, multiplex angiofibromas faciei adesse possunt in conditionibus (multiple endocrine neoplasia type 1 (MEN-1) et Birt-Hogg-Dubé syndrome). Pearly penile papules in margine coronali et sulco penis reperiuntur. Pervicaces, sine dolore, plerumque in praeputio virorum apparent. Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
I) in facie – Papula fibrosa (Fibrous papule)
II) in penis – Papula penialis perlata (Pearly penile papule)
III) sub unguis vel ungula – Angiofibroma periungualis (Periungual angiofibroma)