Basal cell carcinoma - Basalis Cellula Carcinomahttps://la.wikipedia.org/wiki/Epithelioma_basocellulare
Basalis Cellula Carcinoma (Basal cell carcinoma) est frequentissimum genus cancere cutis. Saepe sine dolore dura cutis area apparet. Laesio nitida potest habere venas venas superfluentes. Potest etiam in ulcere levatum. Cancer basalis cellae lente crescit et textus circa eam laedere potest, sed verisimile est provenire in metastasi vel morte.

Periculi factores nuditatem includunt ad lucem ultravioletam, radialem justo, diuturnum expositionem ad munus arsenicum et pauperes immune systematis (v.g. organi transplantationis). Patefacio ad UV lucem in adulescentia maxime nocet.

Post diagnostionem biopsy, curatio proprie est per remotionem chirurgicam. Idque excidere potest, si exiguus cancer est; Si cancer non parvus est, plerumque chirurgica Mohs commendatur.

Carcinoma basalis cellulae saltem 32% omnium carcinomata in globally computat. Carcinomata cutis praeter melanoma circiter 80% sunt carcinomata basali-cellaria. In Civitatibus Foederatis, circiter 35% mares albas et 25% feminarum albarum, afficiuntur carcinomate cellula basali aliquando in vita sua.

Diagnosis et curatio
#Dermoscopy
#Skin biopsy
#Mohs surgery
☆ In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
  • Laesiones exulceratae quae cutem narium in singulis senibus afficiunt saepe dignoscuntur sicut Basalis Cellula Carcinoma (Basal cell carcinoma). Nasus communis locus occurrentis est ad hoc genus cancere cutis.
  • Basalis Cellula Carcinoma (Basal cell carcinoma) terminis irregularibus et ulceribus exhibere possint.
  • Basalis Cellula Carcinoma (Basal cell carcinoma) vulgo misdiagnosed ut nevus in Asianis. Pigmented basal cell carcinoma saepe occurrit in naso.
  • Suspicari debet Basalis Cellula Carcinoma (Basal cell carcinoma) si durum nodulum in limbo prominentem eminens observetur.
  • Basalis Cellula Carcinoma (Basal cell carcinoma) irregularem figuram asymmetricam habet. Hi casus saepe indistincti sunt sicut an intradermal nevus.
  • intradermal nevus misdiagnori potest.
  • Basalis Cellula Carcinoma (Basal cell carcinoma) verruca falli potest.
  • Carcinoma basalis cellula etiam in ulceris forma apparere potest. In hoc casu, distingui debet a carcinomate squamosa.
  • In Occidentalibus, Basalis Cellula Carcinoma (Basal cell carcinoma) sicut nodulus ferreus cum telangiectasia apparet.
  • Basalis Cellula Carcinoma (Basal cell carcinoma) figuram similem habet nota naevi, sed id quod laesio est nodulus durus, interest ut a nevo discernatur.
  • Dum nevus intradermalis (benignus) similis sit, interest notare laesionem Basalis Cellula Carcinoma (Basal cell carcinoma) difficile esse.
  • In Asianis, casus typicus ex Basalis Cellula Carcinoma (Basal cell carcinoma) apparet sicut nodulus niger solidum cum limbo prominente
  • Basalis Cellula Carcinoma (Basal cell carcinoma) a melanoma distingui debet sicut Basalis Cellula Carcinoma (Basal cell carcinoma) multo melius prognosis quam melanoma.
  • Si hae diffusae inaequaliter firmae ad tactum sunt, valde diagnosis Superficial basal cell carcinoma indicat.
  • intradermal nevus misdiagnori potest.
References Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management 26029015 
NIH
Basal cell carcinoma (BCC) Est frequentissimum genus cancere cutis. Solis nulla causa est principalis. Fere omnes BCC casus ericatrices hedgehog ostendunt signum in analysi hypothetica. Variae curationes praesto sunt et electae secundum recursu periculum, momentum textus conservationis, patientis praeferentiae, et amplitudo morbi.
Basal cell carcinoma (BCC) is the most common malignancy. Exposure to sunlight is the most important risk factor. Most, if not all, cases of BCC demonstrate overactive Hedgehog signaling. A variety of treatment modalities exist and are selected based on recurrence risk, importance of tissue preservation, patient preference, and extent of disease.
 Update in the Management of Basal Cell Carcinoma 32346750 
NIH
Basal cell carcinomas Frequentissima sunt cancri cutis in adultis pulchre-cutis 50 et supra longis. Eorum numeros in orbem terrarum oriuntur, maxime ob expositionem solis. Quaedam condiciones geneticae facile possunt efficere ut haec carcinomata in minore aetate enucleentur. Basal cell carcinomas In severitate variantur, ex facili tractabili laesiones superficiales vel nodulares ad ampliora quae discussionem requirunt in specialibus iunctionibus medicis. Prognosis pendet a probabilitate cancri reddendi vel eius facultatem laedendi prope textus. Surgeria est norma curatio in pluribus casibus, praecise remotionis et casus humilitatis recurrentis. Modi incursivi minus efficaciter laesiones superficiales tractare possunt.
Basal cell carcinomas are the most frequent skin cancers in the fair-skinned adult population over 50 years of age. Their incidence is increasing throughout the world. Ultraviolet (UV) exposure is the major carcinogenic factor. Some genodermatosis can predispose to formation of basal cell carcinomas at an earlier age. Basal cell carcinomas are heterogeneous, from superficial or nodular lesions of good prognosis to very extensive difficult-to-treat lesions that must be discussed in multidisciplinary committees. The prognosis is linked to the risk of recurrence of basal cell carcinoma or its local destructive capacity. The standard treatment for most basal cell carcinomas is surgery, as it allows excision margin control and shows a low risk of recurrence. Superficial lesions can be treated by non-surgical methods with significant efficacy.
 European consensus-based interdisciplinary guideline for diagnosis and treatment of basal cell carcinoma-update 2023 37604067
Curatio prima BCC chirurgica est. Pro magno periculo vel BCC frequentissima, praesertim in locis criticis, micrographice chirurgia moderata commendatur. Aegris cum humili periculo superficiali BCC tractationes topicas vel modos perniciosos considerare posset. Lorem photodynamica bene operatur ad periculum nodulare superficialis et humilis BCCs. Pro localiter provecto vel metastatico BCC, Hedgehog inhibitores (vismodegib, sonidegib) commendantur. Si morbus progressio vel intolerantia inhibentium Hedgehog est, immunotherapy cum anti-PD1 antibody (cemiplimab) considerari potest. Radiotherapia optima est optio aegris qui chirurgicam habere non possunt, praesertim aegros maiores. Electrochemotherapy considerari potest si chirurgia vel radiotherapia optionis non est.
The primary treatment for BCC is surgery. For high-risk or recurring BCC, especially in critical areas, micrographically controlled surgery is recommended. Patients with low-risk superficial BCC might consider topical treatments or destructive methods. Photodynamic therapy works well for superficial and low-risk nodular BCCs. For locally advanced or metastatic BCC, Hedgehog inhibitors (vismodegib, sonidegib) are recommended. If there's disease progression or intolerance to Hedgehog inhibitors, immunotherapy with anti-PD1 antibody (cemiplimab) can be considered. Radiotherapy is a good option for patients who can't have surgery, especially older patients. Electrochemotherapy could be considered if surgery or radiotherapy isn't an option.