Dysplastic nevus
☆ In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
Dysplastic nevi ― Biopsy commendatur pro Occidentalibus.
References
Dysplastic nevus , quae atypica vel Clarks nevus appellata est, disputationes in dermatologia et dermatopathologia commovit. Medici saepe biopsy hae talpae, quia abnormes spectare possunt et curas de melanoma erigere possunt.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi , quae atypica vel Clark nevi nota est, interdum melanoma ducere potest. Circa 36% melanomatum prope nevi dysplasticae inveniuntur. Signa quae nevus dysplasticus in melanoma convertat figuram inaequalem includunt, mutationes magis pigmentariae vel colore griseo. Haec carcinomata plerumque in aetate minore (circa medium triginta) fieri possunt, et saepe in stipite esse possunt. Genere, dysplastic nevi sunt inter benigna nevi et melanoma. Tamen tantum 20% ad 30% melanomatum ex nevi existentibus veniunt. Cum maxime nevi melanoma non fiunt, solet non commendari eas praecavendo removere.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Melanoma genus tumoris est quod melanocytes formans, cellulae coloris cutis, carcinomati similem fiunt. Melanocytes a crista neurali originem trahit. Hoc significat melanomas non solum in cute sed etiam in aliis locis ubi cristae cellae neural migrant, sicut tractus gastrointestinalis et cerebrum. Salvus pro aegris cum melanoma praematuro stadio (0 scaenae) altus est ad 97%, dum signanter ad circiter 10% decidit pro illis morbis scaenae aetatis praecognitis (scaena IV) .
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Cancer periculum
Sicut in personis Caucasiis in Iunctus Civitas, illi cum nevi dysplasticis vitam habent, periculum melanoma maius quam 10% evolutionis habent. E contra, illi sine ullo nevo dysplastico periculum melanoma minus quam 1% evolutionis habent.
○ Cautio de personis dysplasticis nevi
Pellis auto-examinatio plerumque commendatur ad melanoma praecavendum (exprimendo nevi atypicam quae removeri potest) vel detectio primorum tumorum exsistentium. Homines cum historia personali vel familiae cancri pellis vel nevi atypici multiplex videre debent dermatologum saltem semel in anno ut fideles melanoma non enucleent.
Abbreviatio [ABCDE] utilis fuit ad provisores sanitatis adiuvandos et laicos memores praecipuorum notarum melanomatis. Infeliciter persona mediocris, multi keratoses seborrheici, quidam lentigines seniles, immo verrucas notas habere possunt, et a melanoma discerni non possunt.
○ [ABCDE]
Asymmetrical: Vitium cutis asymmetrica.
BorderTerminus vitii est irregularis.
Color: melanomas plerumque plures irregulares colores habere.
DiameterNevi major quam 6 mm magis verisimile melanomas quam nevi minores.
Evolution: the evolution (i.e. change) of a nevus or laesion may indicate that the laesion is becoming malignant.