Intraepithelial carcinoma (Bowen disease) - Intraepithelial Carcinoma (Morbus Bowen)https://en.wikipedia.org/wiki/Squamous_cell_skin_cancer
Intraepithelial Carcinoma (Morbus Bowen) (Intraepithelial carcinoma (Bowen disease)) cellulae squamae atypicae ostendit per totam epidermidis crassitudinem proliferatam. Totus tumor epidermide coarctatur neque in dermidem incurrit. Hic morbus technice carcinomati similis indicatur, sed carcinomata communium non-invasivorum dissimilis. (i.e. est cancer cum bono deplorato).

Solet apparet ut erythematous, squamosus vel tetricis regio alicubi in corpore. Locus communis crurum est.

Sanabilis est per varias curationes optiones, ut cryotherapy, curettagia, cauteria, therapia photodynamica, vel laesio excisio.

Diagnosis et curatio
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy
☆ In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
  • Casus typicus Intraepithelial Carcinoma (Morbus Bowen) (Intraepithelial carcinoma (Bowen disease)) misdiagnosus potest esse ut diuturnus, scabie non-scanescens.
  • Cutaneous horn ― Dissimilis verrucis, nodulum durum sistit, et biopsy malignitatem excludendam necesse est.
  • Si vulnus longius manet, cancer cutis considerari debet.
  • Intraepithelial Carcinoma (Morbus Bowen) (Intraepithelial carcinoma (Bowen disease)) casus typicus
  • In hoc casu etiam Irritated seborrheic keratosis diagnosis differentialis potentiale considerari potest.
  • Saepe fallitur pro allergic inordinatione (exempli gratia nummular eczema).
  • Intraepithelial Carcinoma (Morbus Bowen) (Intraepithelial carcinoma (Bowen disease)) casus typicus
  • Alius casus typicus exhibet similes notas morphologicas ad condiciones allergicas.
References Bowen's Disease 35287414 
NIH
Bowen's disease (BD) Est genus canceris cutis quae incipit in tegumen cutis (epidermis) . Communius est in Caucasiis et saepe in locis soli expositis occurrit, sed alibi quoque apparere potest. BD typice ostendit quasi unum vitium. BD saepe visum est ut praenuntius priusquam gravioris generis cancer cutis incidit. Ad egritudinem BD, medici plerumque nituntur in examinandis exemplis sub microscopio (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
 Bowen disease - Case reports 17001052 
NIH
Bowen's disease Maxime afficit albos homines senes super 60. Claves periculorum factores includunt diuturnum tempus solis detectio, ratio immunis infirma, arsenica detectio, et infectio cutis HPV. HPV cantilenae 16, 18, 34, et 48 coniunctae sunt cum Bowen morbo in locis genitalibus. HPV implicatio in casibus non-genialibus minus clara est.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.