Keloid
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In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
Keloidum postoperativum in carpo qui cum injectione triamcinoloni intra‑lesionali tractatus est. Erythema submersum est in regione sinistra tractata.
Keloid posterior auricularis (Posterior auricular Keloid)
Keloids in plantis ambulandum incommoda esse possunt. Injectiones steroides intralesionales pluries peraguntur solent.
Keloids solent in variis partibus corporis observari.
Typica manifestatio thoracis keloides (keloids).
relevance score : -100.0%
ReferencesKeloides resultent ex sanatione anomala post laesionem cutis vel inflammationem. Factores genetici et environmentalium ad progressionem eorum conferunt, cum incidunt magis in personis cum cute obscura, quae sunt Africani, Asiaticae, et Hispanicae. Keloides fiunt, cum fibroblastae nimis activi sunt, collagenem et factores incrementi excessivos producunt. Hoc ducit ad formationem fasciculorum collagenorum abnormalium, quae collagenum keloidale appellantur, cum incremento fibroblastarum. Keloides firmae apparent, noduli elastici in locis antea laesi. Dissimiles a cicatricibus normalibus, keloides ultra locum trauma originalis extendunt. Patiuntur aegroti dolorem, pruritum, vel ustionem. Variae curationes praesto sunt, inter injectiones steroides, cryotherapy, chirurgiam, radiotherapiam, et therapia laser.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Investigatio hodiernae suggerit silicone gel vel tegmen una cum injectionibus corticosteroideis curationem initialem praeferri pro keloidibus. Additae curationes sicut intralesionales 5‑fluorouracil (5‑FU), bleomycin vel verapamil considerari possunt, etsi eorum efficacia variatur. Laser therapia, cum injectionibus corticosteroidibus vel steroidibus topicis sub occlusione conjuncta, accessionem medicamentorum augere potest. Excisio keloidorum cum immediate radiotherapia post‑excisionem optio efficax est pro lesionibus recalcitrantibus. Denique, silicone tegmen et pressio therapia probatae sunt, et probabilitas recidivae keloidorum diminuitur.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
In statu, nulla vis omnis curatio est quae constanter humilem recursum spondet pro keloidibus. Optiones autem crescentes, sicut lasers cum steroidibus utentes, vel 5-fluorouracil cum steroidibus iungentes, promittunt pollicentes. Future investigationes inspicere potuerunt quam bene novas curationes, ut autologum pingue insitionis aut caulis cellae therapiae substructae, opus keloidei administrandi.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
Cicatrices sunt pars naturalis et normalis processus sanationis post iniuriam systematis integumentarii. Cicatrices debent esse planae, tenues, et coloris cutis aequae. Plures factores ad sanationem vulnerum pauperem conferre possunt, inter infectionem, deficiens fluxus sanguinis, ischemiam, et trauma. Cicatrices proliferantes, hyperpigmentatae, aut contractae graves difficultates cum functione corporis et valetudine animi afferre possunt.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
cicatrices keloidales frequentius conspiciuntur in populis Africanis, Asiaticis vel Hispanicis descensus. Homines inter annos X et XXX annorum maiori inclinatione ad keloides quam senes.
Etsi plerumque in situ iniuriae occurrunt, etiam sponte keloides oriri possunt. Possunt in situ perforationis et etiam ex re simplici ut papula vel abrasione. Possunt evenire ex gravi acne vel varicellae cicatrice, infectio in situ vulneris, trauma repetita ad aream, tensio nimia cutis in vulnere clausurae vel ex corpore externo in vulnere.
Cicatrices keloidales post chirurgiam possunt evolvi. Communiores sunt in quibusdam locis, ut pectus centrale (ex sternotomia), dorsum et scapulas (plerumque ex acne oriundae), et lobi aurium (ex perforatione auriculae). Possunt etiam in aliorum corporum perforationibus. Loca frequentissima sunt lobuli aurium, brachia, regio pelvis, et supra claviculam.
Curae in promptu sunt pressio therapia, silicone gel vel pellicula, triamcinolona acetonida intra‑lesionalis, cryosurgia, radiatio, therapia laser, interferon, 5‑FU et chirurgica excisio.
○ Curatio
cicatrices hypertrophicae possunt emendari cum 5 ad 10 injectionibus steroideorum intralesionalibus ad intervallum unius mensis.
#Triamcinolone intralesional injection
Therapia laser ad erythemam cum cicatrice adiuncta temptari potest, sed injectiones triamcinolonae etiam erythemam per flattening cicatricis emendare possunt.
#Dye laser (e.g. V-beam)