Keloid
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Keloidis postoperativa in carpo qui cum triamcinolone intralesionali injectione tractata est. ERYTHEMA submersum est in area sinistra tractata area.
Linear Keloids. Cum abdominis in fronte superiore occurrunt, saepe apparent in figura lineari.
Posterior auricularis Keloid
Keloids in plantis ambulandum incommoda esse possunt. Injectiones steroides injectiones pluries peragi solent.
Keloids solent in brachiis observari.
Typica manifestatio thoracis keloids.
References
Keloids formant propter insolitam sanationem post laesionem vel inflammationem cutis. Factores geneticae et environmentales ad progressionem suam conferunt, cum superiores in personis Africanis, Asiaticis et Hispanicis descensu obscurioribus incultis. Keloids fiunt, cum fibroblasts nimis excitati sunt, factores colligenorum et incrementi nimios producentes. Hoc ducit ad formationem fasciculorum, abnormalium collagenarum, quae keloidales collagen vocantur, cum incremento fibroblastarum. Clicoides, keloides firmae apparent, noduli cartilaginei in locis antea laesi sunt. Dissimilis cicatrices normales, keloides ultra locum trauma originalis extendunt. Patiantur aegroti dolorem, pruritum, vel ustionem. Variae curationes in promptu sunt, inter injectiones steroides, cryotherapy, chirurgiae, radiotherapiae, et therapia laser.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Investigatio hodiernae suggerit siliconem gel vel fusa una cum injectionibus corticosteroideis curationem initialem praeferri pro keloidibus. Additae curationes sicut intralesionales 5-fluorouracil (5-FU) , bleomycin vel verapamil considerari possunt, etsi eorum efficacia variatur. Laser therapia, cum injectionibus corticosteroidibus vel steroidibus topicis sub ileon conjuncta, accessionem medicamentorum augere potest. Keloids enim recalcitrat, remotionem chirurgicam sequitur, statim radiophonicus therapiae efficax ostendit. Demum, silicone fusa et pressura adhibita therapia probata est, verisimilitudo keloid recurrentis decrescere.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
In statu, nulla vis omnis curatio est quae constanter humilem recursum spondet pro keloidibus. Optiones autem crescentes, sicut lasers cum steroidibus utentes, vel 5-fluorouracil cum steroidibus iungentes, promittunt pollicentes. Future investigationes inspicere potuerunt quam bene novas curationes, ut autologum pingue insitionis aut caulis cellae therapiae substructae, opus keloidei administrandi.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
Cicatrices sunt communis pars processus sanationis post iniurias cutis. Specimen cicatrices esse debent planae, tenues, et colori cutis aequae. Plures factores ad sanationem vulnerum pauperum ducere possunt, ut infectio, sanguis reducitur, ischemia, et trauma. Cicatrices, quae sunt crassae, obscuriores quam circum cutem, nimiae recusare possunt quaestiones significantes cum functione corporis et sanitate motus causare.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
cicatrices Keloid frequentius conspiciuntur in populis Africanis, Asiaticis vel Hispaniensibus descensus. Homines inter annos X et XXX annorum altiorem inclinationem habent ad explicandum keloidem quam senes.
Etsi plerumque in situ iniuriae accidere possunt, etiam sponte oriri keloid possunt. Possunt in situ pungentes et etiam ex re simplici sicut papulae vel scabrae. Possunt evenire ex gravi acne vel gallinaceorum cicatrice, infectio in situ vulneris, trauma repetita ad aream, tensio nimia cutis in vulnere clausurae vel in corpore externo in vulnere.
Keloid cicatrices post surgery possunt evolvere. Communiora sunt in nonnullis locis, ut pectus centrale (ex sternotomy), dorsum et scapulas (plerumque ex acne oriundae), et lobi aurium (ab aure pungitur). Possunt etiam in corpore pungitur. Maculae frequentissimae sunt auriculae, bracchia, regionis pelvis, et supra os collaris.
Curae in promptu sunt pressione therapia, silicone gel fusa, acetonido triamcinolone intra-lesionali, cryosurgia, radiorum, therapia laser, interfe&is, 5-FU et chirurgica excisio.
○ Curatio
cicatrices hypertrophicae emendare possunt cum 5 ad 10 injectiones steroides intralesionales 1 mensis interstitii.
#Triamcinolone intralesional injection
Laser curatio erythema cum cicatrice adiunctis temptari potest, sed triamcinilone injectiones etiam erythema per adulatione cicatricem emendare possunt.
#Dye laser (e.g. V-beam)