Lymphangioma
Lymphangioma Malformationes systematis lymphatici propriae sunt laesiones cystarum tenues muratas. Malformationes hae in quavis aetate fieri possunt et aliquam partem corporis involvere possunt, sed 90% in pueris minus quam 2 annis occurrunt et caput et collum implicant. Lymphangiomas plerumque ante partum utendo ultrasonographia fetali praecogniti sunt. Lymphangioma acquisita provenire potest ex trauma, inflammatione, vel obstructione lymphatica. Cum nullam possibilitatem malignitatis habent, lymphangiomae solent ob solas causas cosmeticas tractari.
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ReferencesLymphangioma (Lymphangioma) est etiam malformatio lymphatica (LM). Perturbatio vasculorum est praesens a nativitate. Abnormis incrementum textus lymphatici ante et post partum notatur. Lymphangioma afficit circiter 1 in 2000‑4000 hominum, nulla significativa differentia inter genera vel gentes. Pleraque (80‑90 %) praecogniti sunt ante duos annos. Symptomata varii sunt a tumore locali ad abnormitates in canalibus lymphaticis diffusis, interdum ad elephantiasis (elephantiasis). Verbi gratia, lymphangioma in collo et facie potest causare tumorem facialem, in gravibus casibus deformitatem. Cum linguam afficit, potest ducere ad excrescentiam maxillarem et dentes malpositos. In ore et collo, potest causare difficultates spirandi et casus vitae minaces. In oculis, potest causare damnum visionis, motum oculi limitatum, ptosis (ptosis) et exophthalmum (exophthalmos). In membris, lymphangioma potest causare tumor et abnormem incrementum textuum mollium et ossium. Tumor tardius crescit, sed infectiones, mutationes hormonales, vel iniuria possunt incrementum celeritatis provocare, quae pericula vitae minantia ponunt et curationem urgent.
Lymphangioma (lymphatic malformation, LM), a congenital vascular disease, is a low-flow vascular abnormality in lymphatic diseases that is characterized by excessive growth of lymphatic tissue during prenatal and postpartum development. The incidence rate of LM is ~1:2000–4000, with no variation between genders and races. Most patients (80–90%) are diagnosed before the age of two. The clinical manifestations of lymphangioma are quite different among patients, varying from local swelling leading to superficial mass to a large area of diffuse infiltrating lymphatic channel abnormalities resulting in elephantiasis. Cervicofacial LM can cause facial elephantiasis, and in some severe cases, it can lead to serious disfigurement of the face. Tongue LM can lead to mandibular overgrowth and occlusal asymmetry, and oral and cervical LM can cause obstructive acute respiratory distress and life-threatening situations. Orbital LM may lead to decreased vision, decreased extraocular muscle movement, ptosis and exophthalmos. LM of the extremities can trigger swelling or gigantism, accompanied by overgrowth of soft tissue and bones. LM usually grows slowly and steadily, but under certain conditions, such as infection, hormonal changes or trauma, it can grow explosively and become a life-threatening disease requiring immediate treatment.
Lymphangioma (lymphatic malformation, LM), a congenital vascular disease, is a low-flow vascular abnormality in lymphatic diseases that is characterized by excessive growth of lymphatic tissue during prenatal and postpartum development. The incidence rate of LM is ~1:2000–4000, with no variation between genders and races. Most patients (80–90%) are diagnosed before the age of two. The clinical manifestations of lymphangioma are quite different among patients, varying from local swelling leading to superficial mass to a large area of diffuse infiltrating lymphatic channel abnormalities resulting in elephantiasis. Cervicofacial LM can cause facial elephantiasis, and in some severe cases, it can lead to serious disfigurement of the face. Tongue LM can lead to mandibular overgrowth and occlusal asymmetry, and oral and cervical LM can cause obstructive acute respiratory distress and life-threatening situations. Orbital LM may lead to decreased vision, decreased extraocular muscle movement, ptosis and exophthalmos. LM of the extremities can trigger swelling or gigantism, accompanied by overgrowth of soft tissue and bones. LM usually grows slowly and steadily, but under certain conditions, such as infection, hormonal changes or trauma, it can grow explosively and become a life-threatening disease requiring immediate treatment.
In hoc studio retrospectivo recensimus 24 pueros qui lymphangioma habebant et injectionem solutionis bleomycinum a Ianuario MCMXCIX ad Decembrem 2004 tractavimus. Plurimae lesionum (63%) perfectam resolutionem obtinuerunt, 21% bonam responsionem acceperunt et 16% non bene responderunt. Tumor recidivit in duobus patientibus. Alii duo abscessus formati sunt in loco injectionis. Feliciter alias graves difficultates vel effectus laterales non observavimus.
This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.
This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004. Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.
Genera lymphangioma principalia sunt haec – lymphangioma circumscriptum, cavernous lymphangioma, cystic hygroma, lymphangioendothelioma. Haec constituunt circa 26 % tuberculorum benignorum in pueris, sed in adultis minus communia sunt. Lymphangioma circumscriptum, typus frequentissimus, ductus lymphatici per cutem prominentes ostendit, vesiculis clearis fluidum plenis, similes ova ranae, cum edema textus. Plerumque in regionibus cum rete lymphatico abundante, sicut membris, trunco et axilla. A femina LXXI annorum ad nostram clinicam pervenit cum edema persistente amborum crurum, conglomeratis papulis roseis labialibus, pruritu, et lympho aquoso stillante. Omnes papulas chirurgice removimus per labiectomiam bilateralem maiorem, ad gradum Colles' fasciae, servato clitoride et fourchette.
The predominant types of lymphangioma are lymphangioma circumscriptum (LC), cavernous lymphangioma, cystic hygroma, and lymphangioendothelioma. These entities account for approximately 26% of benign vascular tumors in children but are rarer in adults. LC is the most common form of cutaneous lymphangioma and is characterized by superficial lymphatic ducts protruding through the epidermis. This condition results in clusters of clear fluid-filled vesicles resembling frog spawn and associated tissue edema. It is usually found on the proximal extremity, trunk, and axilla, which has an abundant lymphatic system. A 71-year-old female presented to our outpatient clinic with persistent edema of both lower limbs, clusters of pink labial papules, pruritus, and watery lymph oozing. We removed all the papules by performing bilateral major labiectomy down to the level of Colles' fascia, sparing the clitoris and fourchette.
The predominant types of lymphangioma are lymphangioma circumscriptum (LC), cavernous lymphangioma, cystic hygroma, and lymphangioendothelioma. These entities account for approximately 26% of benign vascular tumors in children but are rarer in adults. LC is the most common form of cutaneous lymphangioma and is characterized by superficial lymphatic ducts protruding through the epidermis. This condition results in clusters of clear fluid-filled vesicles resembling frog spawn and associated tissue edema. It is usually found on the proximal extremity, trunk, and axilla, which has an abundant lymphatic system. A 71-year-old female presented to our outpatient clinic with persistent edema of both lower limbs, clusters of pink labial papules, pruritus, and watery lymph oozing. We removed all the papules by performing bilateral major labiectomy down to the level of Colles' fascia, sparing the clitoris and fourchette.
