Syphilis
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Chancres – infectio primaria syphilitica a Treponema pallidum
relevance score : -100.0%
ReferencesSyphilis est morbus sexualiter transmissus per bacterium Treponema pallidum. In hoc studio nos intendimus in aegros (n = 57) aetatibus 18‑68 cum syphilis secundariis.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Syphilis est contagio bacterialis a Treponema pallidum. Varias morbos imitari potest, ideo cognomen ‘great imitator’ merito habet. Syphilis decies centena milia globaliter afficit, sed efficaciter cum penicillino tractari potest.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum syphilis causatur per contactum sexualem vel a matre ad infantem in graviditate. Etiam si simplices probationes ad hunc morbum et curationem cum penicillino diu actuante bene operantur, syphilis magnam quaestionem iterum in orbe terrarum constituunt. Hoc praesertim verum est inter homines qui cum viris (MSM) concumbunt in nationibus magnis et mediis evolutis. Dum nonnullae nationes ignobiles, quae metas syphilis a matre ad infantem transmittendas prohibere conantur, anxietatem excitant inter MSM HIV‑positivos.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Jecur dilatatum: Haec saepe deprehenditur et potest provenire ex regione splenis. Biopsia iecoris sub microscopio opaco examinata praesentiam spirochetae revelare potest. Munus iecoris probatur ut abnormitates manifestentur. Secundum, de Yellowing cutis (Ictericis): Indicatio est morbi hepatici, quod cutem flavam facit, et potest afficere totum corpus. (3) Liquescit nasus: Saepe inter primos signa, plerumque intra primam hebdomadam post partum. (4) Nodi lymphoidei turgidi: Nodi lymphoidei tumor generativus, plerumque sine dolore, sunt etiam communes. (5) Cutis temeraria: Cutis temeraria typice apparet una ad duas septimanas post nasci, cum maculae parvae rubrae vel roseae in dorso, natis, femoribus, plantis pedum. Haec maculae progrediuntur ad desquamationem et formationem crustae.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Diagnosis et curatio
VDRL et RPR adhiberi possunt ad confirmandam infectionem recentem syphilis et cutaneam manifestationem. Examen FTA‑ABS subtilius est et ad confirmandam historiam prioris infectionis adhiberi potest. Penicillinum ad tractandum syphilis adhibetur.