Urticaria pigmentosa
Urticaria pigmentosa est forma cutis mastocytosis frequentissima. Rarus morbus est ex nimia multitudine cellularum mali in cute, quae eruptions vel laesiones in cute irritatae gignunt. Maculae rubrae vel fuscae saepe in cute videntur, typice circa pectus, frontem et dorsum. Hae cellulae mali, cum irritatae (exempli gratia cutis, expositione caloris aut attritu), nimium histaminum gignunt, quae excitant reactionem allergicam quae ducit ad eruptions locatas ad locum irritationis, interdum notatae ut “signum Darier”.
☆ In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
relevance score : -100.0%
ReferencesMastocytosis est conditio in qua excessus cellularum malarum, saepe in variis partibus corporis sicut cutis, medulla ossis et systema digestorium, invenitur. Secundum World Health Organization (WHO), mastocytosis cutanea in tria genera dividitur. Primum genus (mastocytomas) constat ex una vel paucis (≤3) laesionibus. Alterum genus (urticaria pigmentosa) multas laesiones involvit, plerumque inter plus quam 10 et minus quam 100. Ultimum genus manifestatur per cutem late. Urticaria pigmentosa est forma communissima mastocytosis cutaneae in infantibus, sed etiam in adultis occurrere potest. Solet esse conditionem benignam quae in adulescentia saepe melioratur. Mastocytosis adulta est dissimilis; raro viscera urticaria pigmentosa afficit. Notissima proprietas urticariae pigmentosae est praesentia macularum parvarum, scabiosarum, rubro‑brunnearum vel flavo‑brunnearum, saepe alborum. Hae maculae plerumque in adulescentia apparent et per totam vitam permanere possunt.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Puella VI annorum ingressa est cum pluribus maculis atrocoloribus, quae primum in capite apparuerunt, deindeque ad faciem et corpus per sex menses disseminatae sunt. Ea sentit oriri, rubescere et psoras cum pressione admota. Non expertur ruborem, vomitus, fluxiones intestinales, nec sanguinem, nec historiam medicam personalem aut domesticam. Inspectis, multas maculas obscuras in capite, fronte, facie et collo invenimus, cum aliquantulum elevatis, nigricantibus in pectore et dorso. Maculae leviter fricantur ut intumescant et pruriant intra duas minutas, sed signa defluunt intra 15‑20 minutas (Darier's sign).
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
