Urticarial vasculitis - Urticarialis Vasculitis
☆ In anno 2022 Stiftung Warentest ex Germania provenit, satisfactio consumptoria cum ModelDerm paulo minus fuit quam cum consultationibus telemedicinis solutis.
References
Urticarial vasculitis Rara condicio est diuturna vel frequentissima aluum episodiis notata. Cum eius cutis indicia possunt similes alveariis longis, unica sunt, quia alvearia inhaerent circa quattuor saltem horas et post evanescentem maculas causare possunt. Etsi saepe ignotae causae sunt, interdum quibusdam medicamentis, infectionibus, morbis autoimmunes, morbis sanguinis, vel carcinomatis urguetur. Quaedam studia etiam cum COVID-19 et H1N1 flu. Etiam afficit alias partes corporis sicut musculi, renes, pulmones, stomachum et oculos; Dum quaedam species texturae diagnosis confirmare potest, non semper necesse est. Curatio typice incipit cum antibioticis, dapsone, colchicino, vel hydroxychloroquino in levioribus casibus. Ad casus graviores, medicamenta quae systema immune sicut methotrexatum vel corticosteroides supprimunt opus erit. Nuper, therapiae biologicae (rituximab, omalizumab, interleukin-1 inhibitors) promissionem pro casibus duris ostenderunt.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Vir XXXV annorum venit cum XV dierum historia minio, dolent epinyctidas in utroque femur et crurum, cum dolore articulorum. Habuit infectio tractus urinarii per hebdomadam antequam temerarius apparuit. Eius pellis varia tenella, anulosa, partim blanfica, tabulae rubrae in utroque latere femorum et crurum ostendit. Data est prednisolone oralis (40mg/die) hebdomada una cum antihistamine non-dorso (fexofenadine) . Intra septimanam, omnes temones penitus evanuerunt. Temerarii non amplius erant per proximos sex menses regularium -ups reprehendo.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
○ Curatio OTC Medicamenta
Si febris est (corporis temperaturam auctam), commendamus ut quamprimum medicinae operam quaeras.
Suspectus medicamento intermitti debet. (v.g. antibiotica, non-steroidales medicamenta inflammationis anti-inflammatoriae)
Oral antihistamines ut cetirizine vel loratadine ad pruritum.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
OTC steroideis unguentorum inefficax pro vili potentia. Necessaria est ut plus quam septimana ad emendationem applicandam videatur.
#Hydrocortisone ointment