Intraepithelial carcinoma (Bowen disease)
☆ An den 2022 Stiftung Warentest Resultater aus Däitschland war d'Zefriddenheet vum Konsument mam ModelDerm nëmme liicht manner wéi mat bezuelte Telemedizin Konsultatiounen.
Typesch Fall - Intraepithelial carcinoma (Bowen disease) ka falsch diagnostizéiert ginn als laang dauerhaft, net-juckend Ekzeme.
References
Bowen's disease (BD) ass eng Aart vu Hautkriibs, déi an der äusserer Schicht vun der Haut (Epidermis) ufänkt. Et ass méi heefeg an de Kaukasier a geschitt dacks a Gebidder, déi dem Sonneliicht ausgesat sinn, awer et kann och soss anzwousch optrieden. BD weist typesch als eenzeg Läsion op. BD gëtt dacks als Warnschëld ugesinn ier eng méi sérieux Aart vu Hautkriibs entwéckelt. Fir BD ze diagnostizéieren, vertrauen d'Dokteren normalerweis op d'Untersuchung vun Tissueproben ënner engem Mikroskop (Biopsie) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease beaflosst meeschtens wäiss Individuen am Alter iwwer 60. Schlëssel Risikofaktoren enthalen laangfristeg Sonnebelaaschtung, geschwächt Immunsystem, Arsenexpositioun, an Haut HPV Infektioun. HPV Stämme 16, 18, 34, an 48 si mat der Bowen Krankheet an genital Beräicher verbonnen. D'Bedeelegung vum HPV an net-genital Fäll ass manner kloer.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Et erschéngt normalerweis als erythematös, scaly oder crusty Beräich iwwerall um Kierper. Déi heefegst Plaz ass déi ënnescht Been.
Et ass heelbar duerch verschidde Behandlungsoptioune wéi Kryotherapie, Curettage, Cauterie, photodynamesch Therapie oder Ausschnëtt vun der Läsion.
○ Diagnos a Behandlung
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy