Keloid
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An den 2022 Stiftung Warentest Resultater aus Däitschland war d'Zefriddenheet vum Konsument mam ModelDerm nëmme liicht manner wéi mat bezuelte Telemedizin Konsultatiounen.
An den 2022 Stiftung Warentest Resultater aus Däitschland war d'Zefriddenheet vum Konsument mam ModelDerm nëmme liicht manner wéi mat bezuelte Telemedizin Konsultatiounen.
E postoperativ Keloid um Handgelenk, dat mat Triamcinolone intralesionaler Injektioun behandelt gouf. Den gesonken Erythem‑Beräich op der lénker Säit ass dat behandelte Gebitt.
Linear Keloid. Wann se op der lieweschter Front vum Torso optrieden, schéngen se dacks an enger linearer Form.
Keloid am hanneren Ouerbereich
Keloid op de Féiss kann onwuel fir d'Fouss sinn. Intralesional Steroid‑Injektiounen ginn normalerweis e puer Mol gemaach.
Keloiden ginn allgemeng op dem Uewerarm beobachtet.
Typesch Manifestatioun vun Këscht keloids.
relevance score : -100.0%
ReferencesKeloiden bilden sech wéinst ongewéinlecher Heelung no Hautverletzung oder Entzündung. Genetesch an ëmweltfrëndlech Faktoren droen zu hirer Entwécklung bäi, mat méi héijen Tariffer an däischer Haut bei Individuen vun afrikanescher, asiatescher a spuenescher Ofstammung. Keloiden entstinn, wann Fibroblasten iwweraktiv ginn, exzessiv Kollagen a Wuesstumsfaktoren produzéieren. Dëst féiert zu der Bildunge vu grousse, anormale Kollagenbündelen, bekannt als keloidal Kollagen, zesumme mat enger Erhéijung vun de Fibroblasten. Klinisch erschéngen d'Keloiden als fest, gummiknäppchen Knollen a Gebidder, déi virdru blesséiert goufen. Am Géigesaz zu normale Narben verlängeren d'Keloiden iwwer déi ursprénglech Traumaplaz. Patienten kënnen Péng, Jucken oder Brennen erliewen. Verschidde Behandlunge si verfügbar, dorënner Steroidinjektiounen, Kryotherapie, Chirurgie, Radiotherapie a Lasertherapie.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Keloids result from abnormal wound healing in response to skin trauma or inflammation. Keloid development rests on genetic and environmental factors. Higher incidences are seen in darker skinned individuals of African, Asian, and Hispanic descent. Overactive fibroblasts producing high amounts of collagen and growth factors are implicated in the pathogenesis of keloids. As a result, classic histologic findings demonstrate large, abnormal, hyalinized bundles of collagen referred to as keloidal collagen and numerous fibroblasts. Keloids present clinically as firm, rubbery nodules in an area of prior injury to the skin. In contrast to normal or hypertrophic scars, keloidal tissue extends beyond the initial site of trauma. Patients may complain of pain, itching, or burning. Multiple treatment modalities exist although none are uniformly successful. The most common treatments include intralesional or topical steroids, cryotherapy, surgical excision, radiotherapy, and laser therapy.
Déi aktuell Fuerschung suggéiert, datt Silikongel oder Blat zesumme mat Kortikosteroidinjektiounen déi bevorzugt initial Behandlung fir Keloiden ass. Zousätzlech Behandlungen wéi intralesional 5-Fluorouracil (5-FU), Bleomycin oder Verapamil kënnen och berücksichtegt ginn, obwuel hir Effektivitéit variéiert. Lasertherapie, wann se mat Kortikosteroidinjektiounen oder topeschen Steroiden ënner Okklusioun kombinéiert gëtt, kann d'Penetratioun vun Drogen verbesseren. Fir recalcitrant Keloiden huet eng chirurgesch Entfernunge, gefollegt vun direkter Strahlungstherapie, effektiv gewisen. Schlussendlech ass d'Benotzung vu Silikonplacken an Drocktherapie bewisen, datt d'Wahrscheinlechkeet vun Keloid‑Widderhuelung reduzéiert gëtt.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
Current literature supports silicone gel or sheeting with corticosteroid injections as first-line therapy for keloids. Adjuvant intralesional 5-fluorouracil (5-FU), bleomycin, or verapamil can be considered, although mixed results have been reported with each. Laser therapy can be used in combination with intralesional corticosteroids or topical steroids with occlusion to improve drug penetration. Excision of keloids with immediate post-excision radiation therapy is an effective option for recalcitrant lesions. Finally, silicone sheeting and pressure therapy have evidence for reducing keloid recurrence.
De Moment gëtt et keng een-Gréisst-passt-all Behandlung, déi eng konsequent niddereg Widderhuelungsquote fir Keloiden garantéiert. Allerdéngs weisen d'wuesse Optiounen, wéi d'Benotzung vu Laser an Steroiden oder d'Kombinatioun vun 5-Fluorouracil mat Steroiden, villverspriechend Resultater. Zukünftg Fuerschung kéint sech konzentréieren op nei Behandlungen, wéi autologe Fetttransplantatioun oder Stammzell-baséiert Therapien, fir d'Gestioun vun Keloiden ze funktionéieren.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
There continues to be no gold standard of treatment that provides a consistently low recurrence rate; however the increasing number of available treatments and synergistic combinations of these treatments (i.e., laser-based devices in combination with intralesional steroids, or 5-fluorouracil in combination with steroid therapy) is showing favorable results. Future studies could target the efficacy of novel treatment modalities (i.e., autologous fat grafting or stem cell-based therapies) for keloid management.
Narben sinn een gemeinsamen Bestanddeel vum Heelprozess no Hautverletzungen. Idealerweis sollten Narben flaach a dënn sinn an mat der Hautfaarf passen. Vill Faktoren kënnen zu enger schlechter Woundheilung féieren, wéi Infektioun, reduzéiert Bluttfluss, Ischämie an Trauma. Narben, déi déck, méi däischter sinn wéi d'Haut ronderëm, oder exzessiv schrumpfen, kënnen bedeitend Problemer mat der kierperlecher Funktioun an der emotionaler Gesondheet verursaachen.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Scars are a natural and normal part of healing following an injury to the integumentary system. Ideally, scars should be flat, narrow, and color-matched. Several factors can contribute to poor wound healing. These include but are not limited to infection, poor blood flow, ischemia, and trauma. Proliferative, hyperpigmented, or contracted scars can cause serious problems with both function and emotional well-being.
Leit afrikanescher, asiatescher oder spuenescher Ofstamung kréien dacks Keloiden. Leit tëscht 10 an 30 Joer hunn eng méi héich Tendenz, e Keloid z'entwéckelen, wéi eeler.
Obwuel se normalerweis op der Plaz vun enger Verletzung entstinn, kënnen Keloiden och spontan optrieden. Si kënnen op der Plaz vun engem Piercing optrieden a souguer vun eppes sou Einfachen wéi e Pickel oder Schrummen. Si kënnen optrieden als Resultat vu schwéierer Akne oder Waasserpocken‑Narben, Infektioun op enger Wound‑Plaz, widderhollem Trauma an engem Gebitt, exzessiver Hautspännungs beim Wound‑Verschluss oder engem auslännesche Kierper an enger Wonn.
Keloid‑Narben kënnen no enger Operatioun entstinn. Si sinn méi heefeg op e puer Steller, wéi zum Beispill d'Zentralkëscht (vun enger Sternotomie), de Réck a Schëlleren (normalerweis aus Akne) an d'Ouerloben (vu Ouerpiercings). Si kënnen och op Kierperpiercings optrieden. Déi heefegste Steller sinn d'Ouerréng, d'Waffen, d'Beckenregioun an iwwert de Hals.
Verfügbare Behandlungen sinn Drocktherapie, Silikongelplack, intra‑lesional Triamcinolone Acetonid, Kryochirurgie, Stralung, Lasertherapie, Interferon, 5‑FU an chirurgesch Ausschnëtter.
○ Behandlung
Hypertrophesch Narben kënnen mat 5 bis 10 intra‑lesional Steroidinjektiounen a Méint‑Intervall verbessert ginn.
#Triamcinolone intralesional injection
Laserbehandlung kann probéiert ginn fir Erythem, dat mat Narbenbildung verbonnen ass, awer Triamcinolone‑Injektiounen kënnen och d'Erythem verbesseren, andeems d'Narben flach ginn.
#Dye laser (e.g. V-beam)