Panniculitis - Pannikulitis
☆ An den 2022 Stiftung Warentest Resultater aus Däitschland war d'Zefriddenheet vum Konsument mam ModelDerm nëmme liicht manner wéi mat bezuelte Telemedizin Konsultatiounen.
Tuberkulos ass eng vun de bedeitende Ursaachen.
References
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis bilden eng heterogen Grupp vun entzündleche Krankheeten, déi de subkutane Fettgewebe involvéieren. Dës Stéierunge si rar bei Kanner. D'Pannikulitis kann de primäre Prozess an enger systemescher Stéierung oder engem sekundäre Prozess sinn, deen aus enger Infektioun, Trauma oder Belaaschtung fir Medikamenter resultéiert. Déi meescht Aarte vu Pannikulitis hunn déiselwecht klinesch Presentatioun (onofhängeg vun der Ätiologie) , mat zaarten, erythematöse subkutane Knollen.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , Entzündung vum subkutane Fett, stellt sech normalerweis mat entzündlechen Knollen. Erythema nodosum (EN) ass klinesch déi heefegst Form vu Pannikulitis. Wärend bis zu 55% vun EN als idiopathesch ugesi gëtt, enthalen déi heefegst Ursaachen Infektiounen, Drogen, systemesch Krankheeten wéi Sarkoidose an entzündlech Darmkrankheeten, Schwangerschaft a Malignitéit. EN präsentéiert typesch an den Teenager an den 20er, a gëtt méi heefeg bei Weibercher gesinn. Et gëtt dacks vun engem net spezifesche Prodrom vun enger bis dräi Wochen virausgesat, wat Féiwer, Malaise a Symptomer vun enger ieweschter Atmungstrakt Infektioun enthalen. Kutane Läsionen duerno, typesch lokaliséiert op den Extensor Aspekt vun de Gliedmaart. D'Läsioune si schmerzhafte gerundet oder oval, liicht opgehuewe, net ulcerative roude Knollen. Déi genee Pathogenese vun EN ass net verstanen, obwuel ugeholl gëtt aus Oflagerung vun Immunkomplexen an de Venules vun de Septae am subkutane Fett, wat eng neutrophil Pannikulitis verursaacht. Och ouni spezifesch Therapie fir e kausativen Zoustand, entléisst EN ouni Behandlung an de meeschte Fäll.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.
"Erythema nodosum" ass eng Form vun pannikulitis (panniculitis) charakteriséiert duerch zaarten roude Knollen, 1-10 cm, assoziéiert mat systemesche Symptomer dorënner Féiwer, Malaise a Gelenkschmerzen. Nodule kënnen iwwer eng Period vun 2-6 Wochen ofhuelen ouni Geschwüren oder Narben. Erythema nodosum ass mat Infektiounen assoziéiert, dorënner Hepatitis C, EBV an Tuberkulose, Schwangerschaft, Non-Hodgkin Lymphom, a Bauchspeicheldrüs Kriibs.