Syphilis
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Chancres ― primär syphilitesch Infektioun duerch Treponema pallidum
References
Syphilis ass eng sexuell iwwerdrobar Krankheet verursaacht duerch d'Bakterie Treponema pallidum. An dëser Etude konzentréiere mir eis op 57 Patienten am Alter vun 18-68 mat sekundärer Syphilis.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Syphilis ass eng bakteriell Infektioun verursaacht duerch Treponema pallidum. Et kann verschidde Krankheeten mimikéieren, et verdéngt de Spëtznumm great imitator. Syphilis beaflosst nach ëmmer Millioune weltwäit awer kann effektiv mat Penicillin behandelt ginn.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum verursaacht Syphilis duerch sexuelle Kontakt oder vu Mamm zu Puppelchen wärend der Schwangerschaft. Och wann et einfach Tester ginn fir et ze diagnostizéieren an d'Behandlung mat engem laangwieregen Penicillin-Schéiss funktionnéiert gutt, Syphilis gëtt weltwäit erëm e grousse Problem. Dëst ass besonnesch wouer ënner Männer déi Sex mat Männer (MSM) a Länner mat héijen a mëttleren Akommes hunn. Wärend e puer niddreg Akommeslänner WHO Ziler erfëllt hunn fir d'Syphilis vun der Mamm op de Puppelchen ze stoppen, ass et eng beonrouegend Erhéijung vun der Syphilis ënner HIV-positiven MSM.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) Erweidert Liewer: Dëst gëtt dacks fonnt a kann niewent enger erweiderter Milz geschéien. D'Untersuchung vun enger Liewerbiopsie ënner Darkfield Mikroskopie kann d'Präsenz vum Spirochet opdecken. Leberfunktiounstester kënnen Anomalie weisen. (2) Yellowing vun der Haut (Geelzucht) : Ob iergendeen Gesellschaft weist hänkt dovun of wéi vill d'Liewer beaflosst ass. (3) Runny Nose: Oft ee vun den éischte Schëlder, normalerweis bannent der éischter Woch no der Gebuert. (4) Geschwollen Lymphknäppchen: Generaliséierter Schwellung vun Lymphknäppchen, normalerweis schmerzlos, ass och heefeg. (5) Hautausschlag: En Ausschlag erschéngt typesch eng bis zwou Wochen no der Nues. Dir kënnt kleng rout oder rosa Flecken um Réck, Hënner, Oberschenkel a Féisssohlen gesinn. Dësen Ausschlag kann zu Peeling a Krust weidergoen.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ Diagnos a Behandlung
VDRL an RPR kënne benotzt ginn fir déi rezent Infektioun ze bestätegen an op Syphilis ze screenen. FTA-ABS Test ass e méi spezifeschen Test a ka benotzt ginn fir no der viregter Infektiounsgeschicht ze kontrolléieren. Penicillin gëtt benotzt fir Syphilis ze behandelen.