Urticaria pigmentosa
Urticaria pigmentosa ass déi heefegst Form vu kutaner Mastozytose. Et ass eng selten Krankheet verursaacht duerch exzessiv Zuel vu Mastzellen an der Haut, déi Hives oder Läsionen op der Haut produzéieren wann se irritéiert sinn. Roude oder brong Flecken ginn dacks op der Haut gesi, typesch ronderëm d'Këscht, d'Stir a Réck. Dës Mastzellen, wann irritéiert (zB duerch Hautreiwen, Hëtztbelaaschtung), produzéieren ze vill Histamin, ausléisen eng allergesch Reaktioun, déi zu Hives lokaliséiert an d'Reizungsberäich féiert, heiansdo als "Dariers Zeechen" bezeechent.
☆ An den 2022 Stiftung Warentest Resultater aus Däitschland war d'Zefriddenheet vum Konsument mam ModelDerm nëmme liicht manner wéi mat bezuelte Telemedizin Konsultatiounen.
References
Mastocytosis ass eng Bedingung wou et en Iwwerschoss u Mastzellen ass, dacks a verschiddene Kierperdeeler fonnt wéi d'Haut, de Knueweess an d'Verdauungssystem. No der Weltgesondheetsorganisatioun (WHO) , cutaneous mastocytosis kann an dräi Haaptarten kategoriséiert ginn. Déi éischt Zort (mastocytomas) besteet aus solitären oder e puer (≤3) Läsionen. Déi zweet Zort (urticaria pigmentosa) beinhalt verschidde Läsionen, typesch vu méi wéi 10 bis manner wéi 100. Déi lescht Zort weist verbreet Bedeelegung iwwer d'Haut. Urticaria pigmentosa ass déi heefegst Form vu kutaner Mastozytose bei Kanner, awer et kann och bei Erwuessener optrieden. Et ass normalerweis en harmlosen Zoustand deen dacks während der Adoleszenz verbessert. Am Géigesaz zu erwuessene Mastocytose beaflosst urticaria pigmentosa selten intern Organer. Eng ënnerschiddlech Feature vum urticaria pigmentosa ass seng Tendenz fir kleng, juckend, routbrong oder gielbrong Flecken oder Läsionen op der Haut ze verursaachen, allgemeng bekannt als Hives. Dës Flecken erschéngen normalerweis an der Kandheet a kënnen am ganze Liewen daueren.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
E 6 Joer aalt Meedchen ass mat e puer donkelfaarweg Flecken erakomm, déi fir d'éischt op hirem Kopfhaut opgetaucht sinn an sech an de leschte sechs Méint op hiert Gesiicht a Kierper verbreet hunn. Si huet ernimmt datt se fillen, datt se eropgoen, rout ginn a Jucken wann Drock applizéiert gouf. Si huet keng Spülen, Erbrechung, Diarrho oder Keewer erlieft, an hir perséinlech a familiär medizinesch Geschicht hunn keng relevant Hiweiser geliwwert. Bei der Untersuchung hu mir e puer donkel Flecken op hirer Kopfhaut, Stier, Gesiicht an Hals fonnt, zesumme mat liicht opgehuewe donkel Flecken op hirer Këscht a Réck. Liicht reiwen d'Flecken verursaacht datt se innerhalb vun 2 Minutten schwellen an Jucken, awer d'Symptomer verschwonnen bannent 15-20 Minutten (Darier's sign) .
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
