Acne - ສິວ
☆ ໃນປີ 2022 Stiftung Warentest ຜົນໄດ້ຮັບຈາກເຢຍລະມັນ, ຄວາມພໍໃຈຂອງຜູ້ບໍລິໂພກກັບ ModelDerm ແມ່ນຕໍ່າກວ່າການປຶກສາຫາລືທາງດ້ານການປິ່ນປົວທາງໂທລະສັບເລັກນ້ອຍເທົ່ານັ້ນ.
ສິວ ຝ້າ ກະ ຈຸດດ່າງດຳ. ສ່ວນເທິງຂອງ torso ແລະກັບຄືນໄປບ່ອນແມ່ນພື້ນທີ່ທົ່ວໄປຂອງສິວ.
References
ສິວ, ສະພາບຜິວໜັງທີ່ພົບເລື້ອຍທີ່ສຸດໃນສະຫະລັດ, ແມ່ນບັນຫາຜິວໜັງທີ່ອັກເສບຢ່າງຕໍ່ເນື່ອງ. ການປິ່ນປົວມີຈຸດປະສົງເພື່ອແກ້ໄຂສີ່ປັດໃຈຕົ້ນຕໍທີ່ເຮັດໃຫ້ເກີດສິວ: ການຜະລິດໄຂມັນຫຼາຍເກີນໄປ, ການສ້າງຈຸລັງຜິວຫນັງ, ການສ້າງອານານິຄົມຂອງສິວ Propionibacterium, ແລະເຮັດໃຫ້ເກີດການອັກເສບ. ຢາ retinoids ມີປະສິດຕິຜົນໃນການຄຸ້ມຄອງການອັກເສບແລະບໍ່ອັກເສບໂດຍການປ້ອງກັນແລະຫຼຸດຜ່ອນ comedones ໃນຂະນະທີ່ແກ້ໄຂການອັກເສບ. Benzoyl peroxide, ມີຢູ່ຮ້ານຂາຍຢາ, ເປັນສານຂ້າເຊື້ອແບັກທີເຣັຍໂດຍບໍ່ມີການສົ່ງເສີມການຕໍ່ຕ້ານເຊື້ອແບັກທີເລຍ. ໃນຂະນະທີ່ຢາຕ້ານເຊື້ອທີ່ເປັນຢາປົວພະຍາດທາງປາກແລະປາກເຮັດວຽກຢ່າງດຽວ, ການສົມທົບພວກມັນກັບຢາ retinoids ເສີມປະສິດທິພາບຂອງເຂົາເຈົ້າ. ການເພີ່ມ benzoyl peroxide ເຂົ້າໃນການປິ່ນປົວດ້ວຍຢາຕ້ານເຊື້ອຫຼຸດລົງຄວາມສ່ຽງຕໍ່ການຕໍ່ຕ້ານເຊື້ອແບັກທີເລຍ. Isotretinoin ທາງປາກ, ອະນຸມັດສໍາລັບສິວທີ່ຮຸນແຮງແລະແຂງກະດ້າງ, ແມ່ນບໍລິຫານຜ່ານໂຄງການ iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
ການປິ່ນປົວສິວທົ່ວໄປປະກອບມີ benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. ຢາຕ້ານເຊື້ອທາງປາກແມ່ນເປັນສ່ວນຫນຶ່ງທີ່ສໍາຄັນຂອງການປິ່ນປົວສິວ, ໂດຍສະເພາະສໍາລັບກໍລະນີປານກາງເຖິງຮ້າຍແຮງ. ພວກມັນເຮັດວຽກໄດ້ດີທີ່ສຸດເມື່ອໃຊ້ຄຽງຄູ່ກັບຢາ retinoid ແລະ BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin ມີຫຼັກຖານສະແດງປະສິດທິພາບທັງໝົດ.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
ຢາ retinoids ສະເພາະແມ່ນແນະນໍາສະເຫມີສໍາລັບການປິ່ນປົວສິວ. ເມື່ອໃຊ້ຢາຕ້ານເຊື້ອທີ່ເປັນລະບົບຫຼືຢາປົວພະຍາດ, ມັນເປັນສິ່ງສໍາຄັນທີ່ຈະສົມທົບພວກມັນກັບ benzoyl peroxide ແລະ retinoids, ແຕ່ໃຊ້ເວລາເຖິງ 12 ອາທິດເທົ່ານັ້ນ. Isotretinoin ສະຫງວນໄວ້ສຳລັບກໍລະນີທີ່ເປັນສິວຮຸນແຮງທີ່ຍັງບໍ່ທັນຕອບສະໜອງຕໍ່ການປິ່ນປົວອື່ນໆ. ໃນຂະນະທີ່ມີຫຼັກຖານບາງຢ່າງສໍາລັບການປິ່ນປົວທາງດ້ານຮ່າງກາຍເຊັ່ນການປິ່ນປົວດ້ວຍເລເຊີແລະການປອກເປືອກສານເຄມີ, ເຊັ່ນດຽວກັນກັບວິທີການເສີມເຊັ່ນ: ພິດເຜິ້ງທີ່ບໍລິສຸດແລະອາຫານບາງຢ່າງ, ປະສິດທິຜົນຂອງພວກມັນຍັງບໍ່ແນ່ນອນ.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
ການສຶກສາຈໍານວນຫນຶ່ງໄດ້ເບິ່ງວິທີການອາຫານທີ່ແຕກຕ່າງກັນຜົນກະທົບຕໍ່ສິວໃນຄົນເຈັບ. ພວກເຂົາພົບວ່າຜູ້ທີ່ເປັນສິວທີ່ກິນອາຫານທີ່ມີປະລິມານ glycemic ຕ່ໍາມັກຈະມີຈຸດສິວຫນ້ອຍລົງເມື່ອທຽບກັບຜູ້ທີ່ກິນອາຫານທີ່ມີ glycemic ສູງ. ນົມຍັງໄດ້ຮັບການສຶກສາກ່ຽວກັບສິວ. ມັນເບິ່ງຄືວ່າທາດໂປຼຕີນບາງຢ່າງໃນນົມອາດຈະປະກອບສ່ວນຕໍ່ສິວຫຼາຍກ່ວາໄຂມັນຫຼືນົມທັງຫມົດ. ການຄົ້ນຄວ້າອື່ນໆໄດ້ສຸມໃສ່ອາຊິດໄຂມັນ omega-3 ແລະອາຊິດγ-linoleic. ມັນຊີ້ໃຫ້ເຫັນວ່າຜູ້ທີ່ມີສິວອາດຈະໄດ້ຮັບຜົນປະໂຫຍດຈາກການກິນປາຫຼາຍແລະນໍ້າມັນທີ່ມີສຸຂະພາບດີເພື່ອເພີ່ມການໄດ້ຮັບອາຊິດໄຂມັນເຫຼົ່ານີ້. ການສຶກສາຫຼ້າສຸດກ່ຽວກັບ probiotics ສໍາລັບສິວສະແດງໃຫ້ເຫັນຜົນໄດ້ຮັບທີ່ດີ, ແຕ່ການຄົ້ນຄວ້າເພີ່ມເຕີມແມ່ນຈໍາເປັນເພື່ອຢືນຢັນການຄົ້ນພົບເບື້ອງຕົ້ນເຫຼົ່ານີ້.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
ໃນທັງສອງເພດ, ຮໍໂມນທີ່ເອີ້ນວ່າ androgens ເບິ່ງຄືວ່າເປັນສ່ວນຫນຶ່ງຂອງກົນໄກທີ່ຕິດພັນ, ໂດຍການເຮັດໃຫ້ການຜະລິດຂອງ sebum ເພີ່ມຂຶ້ນ. ປັດໄຈທົ່ວໄປອີກອັນຫນຶ່ງແມ່ນການຂະຫຍາຍຕົວຫຼາຍເກີນໄປຂອງເຊື້ອແບັກທີເຣັຍ Cutibacterium acnes, ທີ່ມີຢູ່ໃນຜິວຫນັງ.
ການປິ່ນປົວຖືກນໍາໃຊ້ໂດຍກົງກັບຜິວຫນັງທີ່ຖືກກະທົບ, ເຊັ່ນ: ອາຊິດ azelaic, benzoyl peroxide, ແລະອາຊິດ salicylic, ຖືກນໍາໃຊ້ທົ່ວໄປ. ຢາຕ້ານເຊື້ອແລະຢາ retinoids ແມ່ນມີຢູ່ໃນສູດທີ່ໃຊ້ກັບຜິວຫນັງແລະກິນທາງປາກເພື່ອປິ່ນປົວສິວ. ຢ່າງໃດກໍ່ຕາມ, ການຕໍ່ຕ້ານກັບຢາຕ້ານເຊື້ອອາດຈະພັດທະນາເປັນຜົນມາຈາກການປິ່ນປົວດ້ວຍຢາຕ້ານເຊື້ອ. ຢາຄຸມກຳເນີດຫຼາຍຊະນິດອາດຈະຊ່ວຍປ້ອງກັນສິວໃນແມ່ຍິງ. ການປິ່ນປົວສິວໄວແລະຮຸກຮານໂດຍໃຊ້ isotretinoin ອາດຈະຊ່ວຍຫຼຸດຜ່ອນອາການແຊກຊ້ອນໃນໄລຍະຍາວຂອງບຸກຄົນ.
○ ການປິ່ນປົວ
Adapalene gel ສາມາດຖືກນໍາໃຊ້ຢ່າງກວ້າງຂວາງເນື່ອງຈາກວ່າມັນສະກັດກັ້ນຄວາມລັບຂອງ sebum ແລະມີຜົນກະທົບສະກັດກັ້ນການເກີດໃຫມ່ຂອງສິວ. Adapalene gel ສາມາດລະຄາຍເຄືອງຜິວຫນັງຖ້າໃຊ້ຫຼາຍເກີນໄປໃນເບື້ອງຕົ້ນ. Benzoyl peroxide ແລະອາຊິດ azelaic, ໃນທາງກົງກັນຂ້າມ, ສາມາດໃຊ້ກັບສະຖານທີ່ສິວອັກເສບເພາະວ່າພວກມັນຊ່ວຍໃນການອັກເສບ. ໂດຍທົ່ວໄປແລ້ວ, ການປິ່ນປົວໄລຍະຍາວແມ່ນ 1 ເດືອນຫຼືຫຼາຍກວ່ານັ້ນແມ່ນຕ້ອງການເພື່ອເຫັນຜົນ.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction