Intraepithelial carcinoma (Bowen disease)
☆ ໃນປີ 2022 Stiftung Warentest ຜົນໄດ້ຮັບຈາກເຢຍລະມັນ, ຄວາມພໍໃຈຂອງຜູ້ບໍລິໂພກກັບ ModelDerm ແມ່ນຕໍ່າກວ່າການປຶກສາຫາລືທາງດ້ານການປິ່ນປົວທາງໂທລະສັບເລັກນ້ອຍເທົ່ານັ້ນ.
ກໍລະນີທົ່ວໄປ - Intraepithelial carcinoma (Bowen disease) ອາດຈະຖືກວິນິໄສຜິດເປັນ eczema ດົນນານ, ບໍ່ມີອາການຄັນ.
References
Bowen's disease (BD) ເປັນມະເຮັງຜິວໜັງຊະນິດໜຶ່ງທີ່ເລີ່ມຢູ່ໃນຊັ້ນນອກຂອງຜິວໜັງ (epidermis) . ມັນພົບເລື້ອຍໃນຊາວ Caucasians ແລະມັກຈະເກີດຂື້ນໃນບ່ອນທີ່ຖືກແສງແດດ, ແຕ່ມັນກໍ່ສາມາດປາກົດຢູ່ບ່ອນອື່ນເຊັ່ນກັນ. BD ປົກກະຕິແລ້ວສະແດງໃຫ້ເຫັນເຖິງເປັນ lesion ດຽວ. BD ມັກຈະເຫັນວ່າເປັນສັນຍານເຕືອນກ່ອນທີ່ຈະເປັນມະເຮັງຜິວໜັງຊະນິດຮ້າຍແຮງກວ່າຈະພັດທະນາ. ເພື່ອວິນິດໄສ BD, ທ່ານ ໝໍ ມັກຈະອີງໃສ່ການກວດກາຕົວຢ່າງເນື້ອເຍື່ອພາຍໃຕ້ກ້ອງຈຸລະທັດ (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease ສ່ວນຫຼາຍແມ່ນມີຜົນກະທົບກັບຄົນຜິວຂາວທີ່ມີອາຍຸຫຼາຍກວ່າ 60 ປີ. ປັດໃຈສ່ຽງຫຼັກລວມມີການຖືກແດດໃນໄລຍະຍາວ, ລະບົບພູມຄຸ້ມກັນອ່ອນແອ, ການໄດ້ຮັບສານອາເຊນິກ, ແລະການຕິດເຊື້ອ HPV ຜິວຫນັງ. ເຊື້ອ HPV ສາຍພັນ 16, 18, 34, ແລະ 48 ແມ່ນຕິດພັນກັບພະຍາດ Bowen ໃນບໍລິເວນອະໄວຍະວະເພດ. ການມີສ່ວນຮ່ວມຂອງ HPV ໃນກໍລະນີທີ່ບໍ່ແມ່ນອະໄວຍະວະເພດແມ່ນມີຄວາມຊັດເຈນຫນ້ອຍ.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
ມັນມັກຈະປາກົດເປັນບໍລິເວນທີ່ເປັນຕາເປັນເກັດໆ, ເປັນເກັດ ຫຼືເປັນເກັດໆຢູ່ທຸກບ່ອນໃນຮ່າງກາຍ. ສະຖານທີ່ທົ່ວໄປທີ່ສຸດແມ່ນຂາຕ່ໍາ.
ມັນສາມາດປິ່ນປົວໄດ້ໂດຍທາງເລືອກໃນການປິ່ນປົວຕ່າງໆເຊັ່ນ: ການປິ່ນປົວດ້ວຍ cryotherapy, curettage, cautery, photodynamic therapy, ຫຼື excision ຂອງ lesion.
○ ວິນິດໄສ ແລະການປິ່ນປົວ
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy