ຂໍ້ມູນເພີ່ມເຕີມ ― Lao

Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.

Panniculitis ປະກອບເປັນກຸ່ມຂອງພະຍາດອັກເສບ heterogenous ທີ່ກ່ຽວຂ້ອງກັບເນື້ອເຍື່ອ adipose subcutaneous. ຄວາມຜິດປົກກະຕິເຫຼົ່ານີ້ແມ່ນຫາຍາກໃນເດັກນ້ອຍ. ໂຣກ panniculitis ສາມາດເປັນຂະບວນການຕົ້ນຕໍໃນຄວາມຜິດປົກກະຕິຂອງລະບົບຫຼືຂະບວນການທີສອງທີ່ເປັນຜົນມາຈາກການຕິດເຊື້ອ, ການບາດເຈັບຫຼືການໄດ້ຮັບຢາ. ປະເພດຂອງໂຣກ panniculitis ສ່ວນໃຫຍ່ມີການນໍາສະເຫນີທາງດ້ານການຊ່ວຍດຽວກັນ (ໂດຍບໍ່ຄໍານຶງເຖິງ aetiology) , ທີ່ມີ nodules subcutaneous ອ່ອນໂຍນ, erythematous.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.

Panniculitis , ການອັກເສບຂອງໄຂມັນໃຕ້ຜິວໜັງ, ມັກຈະມີຕ່ອມອັກເສບ. Erythema nodosum (EN) ແມ່ນເປັນຮູບແບບຂອງ​โรค​ panniculitis ເລື້ອຍໆ. ໃນຂະນະທີ່ເຖິງ 55% ຂອງ EN ຖືກພິຈາລະນາເປັນ idiopathic, ສາເຫດທົ່ວໄປທີ່ສຸດປະກອບມີການຕິດເຊື້ອ, ຢາເສບຕິດ, ພະຍາດລະບົບເຊັ່ນ: sarcoidosis, ມະເລກຕະວັນ (pancreatic cancer), ການຖືພາ, ມະເລກບໍ່ມີພະນັກສັງກັບ (non‑Hodgkin lymphoma). ໂດຍທົ່ວໄປແລ້ວ EN ປະກົດຢູ່ໃນໄວໜຸ່ມ ແລະ 20s, ແລະແມ່ນເຫັນໄດ້ເລື້ອຍໆໃນເພດຍິງ. ມັນມັກຈະຖືກນໍາຫນ້າໂດຍ prodrome ທີ່ບໍ່ສະເພາະຂອງຫນຶ່ງຫາສາມອາທິດ, ເຊິ່ງອາດຈະປະກອບມີໄຂ້, malaise, ແລະອາການຂອງການຕິດເຊື້ອທາງຫາຍ່ອງອາກາດ. ຫຼັງຈາກນັ້ນ, ຜິວຜົນຕາມມາ, ດ້ວຍປົກກະຕິແມ່ນຕັ້ງຢູ່ໃນສ່ວນຂະໜາດຂອງແຂນແລະຂາ. ກອດແມ່ນເປັນຮູບກົມ ຫຼື ຮູບໂຕອອກ, ຍົກຂຶ້ນມາເລັກນ້ອຍ, ເປັນຕຸ່ມສີແດງບໍ່ແກ່ຂອງຜິວ. ການເກີດພະຍາດທີ່ແນ່ນອນຂອງ EN ແມ່ນບໍ່ເຂົ້າໃຈ, ເຖິງແມ່ນວ່າຄິດວ່າເປັນຜົນມາຈາກອິມູນຊັດຕໍ່ກັນຂອງສະລັບສັບຊ້ອນໃນ venules ຂອງ septae ໃນໄຂມັນ subcutaneous, ເຊິ່ງກໍ່ໃຫ້ເກີດ panniculitis neutrophilic. ເຖິງແມ່ນບໍ່ມີການປິ່ນປົວສະເພາະສໍາລັບເງື່ອນໄຂທີ່ເປັນສາເຫດ, EN ແກ້ໄຂໂດຍບໍ່ມີການປິ່ນປົວໃນກໍລະນີຫຼາຍທີ່ສຸດ.
Panniculitis, inflammation of the subcutaneous fat, usually presents with inflammatory nodules. Erythema nodosum (EN) is clinically the most frequent form of panniculitis. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded by a non-specific prodrome of one to three weeks, which may include fever, malaise, and symptoms of an upper respiratory tract infection. Cutaneous lesions then follow, typically localized on the extensor aspect of the limbs. The lesions are painful rounded or oval, slightly raised, non-ulcerative red nodules. The exact pathogenesis of EN is not understood, although is thought to result from deposition of immune complexes in the venules of the septae in subcutaneous fat, causing a neutrophilic panniculitis. Even without specific therapy for a causative condition, EN resolves without treatment in most cases.