Staphylococcal scalded skin syndrome
☆ ໃນປີ 2022 Stiftung Warentest ຜົນໄດ້ຮັບຈາກເຢຍລະມັນ, ຄວາມພໍໃຈຂອງຜູ້ບໍລິໂພກກັບ ModelDerm ແມ່ນຕໍ່າກວ່າການປຶກສາຫາລືທາງດ້ານການປິ່ນປົວທາງໂທລະສັບເລັກນ້ອຍເທົ່ານັ້ນ.
References
Staphylococcal Scalded Skin Syndrome ເປັນສະພາບທີ່ຜິວໜັງຫຼົ່ນລົງຍ້ອນສານພິດທີ່ຜະລິດຈາກເຊື້ອແບັກທີເຣັຍ Staphylococcus ບາງຊະນິດ. ເປັນເລື່ອງແປກທີ່ໃນເດັກນ້ອຍອາຍຸເກີນ 6 ປີ. ມັນຍັງສາມາດເກີດຂື້ນໃນຜູ້ໃຫຍ່ທີ່ມີລະບົບພູມຕ້ານທານອ່ອນແອຫຼືບັນຫາຫມາກໄຂ່ຫຼັງທີ່ຮ້າຍແຮງ. ຄຸນນະສົມບັດຕົ້ນຕໍແມ່ນການປອກເປືອກຜິວຫນັງຢ່າງກວ້າງຂວາງຫຼັງຈາກການອັກເສບ. ຄວາມຮຸນແຮງແມ່ນຕັ້ງແຕ່ຕຸ່ມຜື່ນເລັກນ້ອຍຈົນເຖິງການສູນເສຍຜິວຫນັງທີ່ກວ້າງຂວາງ, ເຊິ່ງສາມາດເຮັດໃຫ້ອຸນຫະພູມຮ່າງກາຍຫຼຸດລົງຢ່າງຮຸນແຮງແລະຄວາມບໍ່ສະຖຽນລະພາບຂອງຄວາມດັນເລືອດ.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
ເດັກນ້ອຍອາຍຸ 10 ເດືອນ ມີອາການນ້ຳມູກໄຫຼ ແລະ ກິນອາຫານບໍ່ແຊບ. ທ່ານໝໍກ່າວວ່າ ມັນເປັນການຕິດເຊື້ອທາງເດີນຫາຍໃຈທາງເທິງ. ສອງມື້ຕໍ່ມາ, ລາວກັບມາຍ້ອນບໍ່ດີຂຶ້ນ ແລະມີບັນຫາໃໝ່ໆເຊັ່ນ: ໃບໜ້າບວມ ແລະ ຜິວໜັງຮອບປາກ. ໃນສອງມື້ຕໍ່ມາ, ເດັກຊາຍໄດ້ຮ້າຍແຮງຂຶ້ນ. ແຂນ ແລະຂາຂອງລາວບວມຂຶ້ນ ແລະຜິວໜັງຂອງລາວເລີ່ມອອກ. ກັບຄືນໄປໂຮງໝໍ, ທ່ານໝໍໄດ້ສັງເກດເຫັນຕຸ່ມຜື່ນແດງຢູ່ໜ້າຂອງລາວ ແລະຕາມຮອຍຂອງຜິວໜັງຂອງລາວ, ເຊິ່ງມີຮອຍແປ້ວເມື່ອຖືກແຕະຕ້ອງ. ພວກເຂົາເຈົ້າໄດ້ກວດພົບລາວເປັນ staphylococcal scalded skin syndrome (SSSS) ແລະໄດ້ເລີ່ມຕົ້ນໃຫ້ເຂົາກ່ຽວກັບຢາຕ້ານເຊື້ອໂດຍຜ່ານເສັ້ນເລືອດ.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
ເດັກຍິງອາຍຸ 2 ປີຄົນໜຶ່ງມີຜື່ນແດງຂຶ້ນທົ່ວຮ່າງກາຍທີ່ເກີດຂຶ້ນໃນເວລາ 48 ຊົ່ວໂມງ, ຫຼັງຈາກແມງໄມ້ກັດຢູ່ເທິງໃບໜ້າໃນມື້ກ່ອນ. ໃນລະຫວ່າງການກວດ, ນາງມີຕຸ່ມຜື່ນທີ່ແຜ່ລາມອອກເປັນຕຸ່ມນ້ອຍໆທີ່ລວມເຂົ້າກັນ, ແລະເມື່ອຖືກຖູເບົາໆ, ຜິວຫນັງຂອງນາງໄດ້ສະແດງອາການຂອງ Nikolsky. ບໍ່ມີອາການຂອງຜື່ນທີ່ສົ່ງຜົນກະທົບຕໍ່ເຍື່ອເມືອກຂອງນາງ. ການກວດເລືອດຂອງນາງບໍ່ໄດ້ສະແດງອາການຂອງການຕິດເຊື້ອ.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
ໂຣກດັ່ງກ່າວຖືກກະຕຸ້ນໂດຍ exotoxins epidermolytic (exfoliatin) A ແລະ B, ເຊິ່ງຖືກປ່ອຍອອກມາໂດຍ S. aureus. ການຄາດຄະເນຂອງ staphylococcal scalded skin syndrome ໃນເດັກນ້ອຍແມ່ນດີເລີດ, ມີການແກ້ໄຂຢ່າງສົມບູນພາຍໃນ 10 ມື້ຂອງການປິ່ນປົວ, ແລະບໍ່ມີຮອຍແປ້ວທີ່ສໍາຄັນ. ຢ່າງໃດກໍ່ຕາມ, staphylococcal scalded skin syndrome ຕ້ອງໄດ້ຮັບການຈໍາແນກຢ່າງລະມັດລະວັງຈາກການເປັນພິດຂອງ epidermal necrolysis, ເຊິ່ງເຮັດໃຫ້ການຄາດຄະເນທີ່ບໍ່ດີ.
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