Syphilis
☆ ໃນປີ 2022 Stiftung Warentest ຜົນໄດ້ຮັບຈາກເຢຍລະມັນ, ຄວາມພໍໃຈຂອງຜູ້ບໍລິໂພກກັບ ModelDerm ແມ່ນຕໍ່າກວ່າການປຶກສາຫາລືທາງດ້ານການປິ່ນປົວທາງໂທລະສັບເລັກນ້ອຍເທົ່ານັ້ນ.
Chancres - ການຕິດເຊື້ອ syphilitic ເບື້ອງຕົ້ນໂດຍ Treponema pallidum
References
ພະຍາດຊີຟີລິດເປັນພະຍາດຕິດຕໍ່ທາງເພດສໍາພັນທີ່ເກີດຈາກເຊື້ອແບັກທີເຣັຍ Treponema pallidum. ໃນການສຶກສານີ້, ພວກເຮົາສຸມໃສ່ຄົນເຈັບ 57 ອາຍຸ 18-68 ທີ່ມີໂຣກsyphilis ມັດທະຍົມ.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
Venereal syphilis is a multi-stage, sexually transmitted disease caused by the spirochetal bacterium Treponema pallidum (Tp). Herein we describe a cohort of 57 patients (age 18-68 years) with secondary syphilis (SS) identified through a network of public sector primary health care providers in Cali, Colombia.
ໂຣກ syphilis ແມ່ນການຕິດເຊື້ອແບັກທີເລຍທີ່ເກີດຈາກ Treponema pallidum. ມັນສາມາດ mimic ພະຍາດຕ່າງໆ, ໄດ້ຮັບຊື່ຫຼິ້ນ great imitator. ພະຍາດຊີຟີລິດຍັງສົ່ງຜົນກະທົບຕໍ່ຫຼາຍລ້ານຄົນໃນທົ່ວໂລກ ແຕ່ສາມາດປິ່ນປົວດ້ວຍຢາເປນີຊີລິນຢ່າງມີປະສິດທິພາບ.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Syphilis is a systemic bacterial infection caused by the spirochete Treponema pallidum. Due to its many protean clinical manifestations, it has been named the “great imitator and mimicker.” Syphilis remains a contemporary plague that continues to afflict millions of people worldwide. Luckily, the causative organism is still sensitive to penicillin.
Treponema pallidum ເຮັດໃຫ້ເກີດພະຍາດ syphilis ໂດຍຜ່ານການຕິດຕໍ່ທາງເພດສໍາພັນຫຼືຈາກແມ່ຫາລູກໃນລະຫວ່າງການຖືພາ. ເຖິງແມ່ນວ່າມີການກວດຫາວິນິດໄສແບບງ່າຍໆ ແລະ ການປິ່ນປົວດ້ວຍການສັກຢາເປນີຊີລິນທີ່ອອກລິດຍາວເທື່ອດຽວກໍເຮັດວຽກໄດ້ດີ, ແຕ່ພະຍາດ syphilis ໄດ້ກາຍເປັນບັນຫາໃຫຍ່ອີກຄັ້ງນຶ່ງໃນທົ່ວໂລກ. ນີ້ແມ່ນຄວາມຈິງໂດຍສະເພາະໃນບັນດາຜູ້ຊາຍທີ່ມີເພດສໍາພັນກັບຜູ້ຊາຍ (MSM) ໃນປະເທດທີ່ມີລາຍໄດ້ສູງແລະປານກາງ. ໃນຂະນະທີ່ບາງປະເທດທີ່ມີລາຍໄດ້ຕໍ່າໄດ້ບັນລຸເປົ້າຫມາຍຂອງ WHO ເພື່ອຢຸດການແຜ່ເຊື້ອໂຣກ syphilis ຈາກແມ່ໄປຫາລູກ, ໂຣກ syphilis ເພີ່ມຂຶ້ນທີ່ຫນ້າເປັນຫ່ວງໃນບັນດາ MSM ທີ່ຕິດເຊື້ອ HIV.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
Treponema pallidum subspecies pallidum (T. pallidum) causes syphilis via sexual exposure or via vertical transmission during pregnancy. Despite the availability of simple diagnostic tests and the effectiveness of treatment with a single dose of long-acting penicillin, syphilis is re-emerging as a global public health problem, particularly among men who have sex with men (MSM) in high-income and middle-income countries. Although several low-income countries have achieved WHO targets for the elimination of congenital syphilis, an alarming increase in the prevalence of syphilis in HIV-infected MSM serves as a strong reminder of the tenacity of T. pallidum as a pathogen.
(1) ຕັບຂະຫຍາຍໃຫຍ່ຂື້ນ: ອັນນີ້ມັກພົບໄດ້ເລື້ອຍໆ ແລະອາດຈະເກີດຂຶ້ນຄຽງຄູ່ກັບການມີກະດູກໃຫຍ່. ການກວດ biopsy ຕັບພາຍໃຕ້ກ້ອງຈຸລະທັດ darkfield ອາດຈະເປີດເຜີຍໃຫ້ເຫັນການມີ spirochete ໄດ້. ການທົດສອບການເຮັດວຽກຂອງຕັບອາດຈະສະແດງໃຫ້ເຫັນຄວາມຜິດປົກກະຕິ. (2) ຜິວໜັງເຫຼືອງ (ພະຍາດເຫຼືອງ) : ຜູ້ໃດຜູ້ໜຶ່ງສະແດງອາການເຫຼືອງແມ່ນຂຶ້ນກັບວ່າຕັບໄດ້ຮັບຜົນກະທົບຫຼາຍປານໃດ. (3) ນ້ຳມູກໄຫຼ: ມັກຈະເປັນໜຶ່ງໃນອາການທຳອິດ, ໂດຍປົກກະຕິແລ້ວພາຍໃນອາທິດທຳອິດຫຼັງເກີດ. (4) ຕ່ອມນ້ຳມູກບວມ: ການບວມຂອງຕ່ອມນ້ຳເຫຼືອງໂດຍທົ່ວໄປແລ້ວ, ໂດຍທົ່ວໄປແລ້ວບໍ່ເຈັບປວດ, ກໍ່ເປັນເລື່ອງທຳມະດາ. (5) ຜື່ນຜິວໜັງ: ໂດຍທົ່ວໄປແລ້ວ ຜື່ນຈະປະກົດຂຶ້ນໜຶ່ງຫາສອງອາທິດຫຼັງຈາກນ້ຳມູກໄຫຼ. ເຈົ້າອາດຈະເຫັນຈຸດສີແດງ ຫຼືສີບົວນ້ອຍໆຢູ່ດ້ານຫຼັງ, ກົ້ນ, ຂາ, ແລະຕີນ. ຜື່ນນີ້ສາມາດກ້າວໄປສູ່ການປອກເປືອກແລະປອກເປືອກ.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
(1) Hepatomegaly: This is the most common finding and may occur with splenomegaly. Biopsy of the liver followed by darkfield microscopy may reveal the spirochete. Liver function tests may be abnormal. (2) Jaundice: Jaundice may or may not be present depending on the extent of liver injury. (3) Rhinitis: One of the first clinical presentations, usually in the first week of life. Copious, persistent white discharge is noted, which contains spirochetes that can be visualized under darkfield microscopy. (4) Generalized Lymphadenopathy: Generalized, non-tender lymphadenopathy is also a common finding. (5) Rash: Rash usually appears one to two weeks after rhinitis. Small red or pink colored maculopapular lesions may be commonly seen on the back, buttocks, posterior thigh and soles of the feet. The rash progresses to desquamation and crusting.
○ ວິນິດໄສແລະການປິ່ນປົວ
VDRL ແລະ RPR ສາມາດຖືກນໍາໃຊ້ເພື່ອຢືນຢັນການຕິດເຊື້ອທີ່ຜ່ານມາແລະຫນ້າຈໍສໍາລັບໂຣກsyphilis. ການທົດສອບ FTA-ABS ແມ່ນການທົດສອບທີ່ສະເພາະກວ່າແລະສາມາດຖືກນໍາໃຊ້ເພື່ອກວດເບິ່ງປະຫວັດການຕິດເຊື້ອທີ່ຜ່ານມາ. Penicillin ແມ່ນໃຊ້ເພື່ອປິ່ນປົວພະຍາດ syphilis.