Melasma
☆ 2022 m. Stiftung Warentest iš Vokietijos rezultatai rodo, kad vartotojų pasitenkinimas ModelDerm buvo tik šiek tiek mažesnis nei mokamų nuotolinės medicinos konsultacijų.
Tai dažna būklė, stebima 40 metų amžiaus Azijos moterims. Apskritas pažeidimas nuotraukoje yra arčiau lentigo, o ne melasmos.
References
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI after treat?ment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma.
Pastaruoju metu low-fluence Q-switched Nd:YAG (LFQSNY) lazeris išpopuliarėjo melazmos gydymui, ypač Azijoje. Apibendrinti įvairius tyrimus buvo sudėtinga, tačiau LFQSNY paprastai atrodo veiksmingas ir saugus melazmai, palyginti su tradiciniais gydymo būdais. Tačiau buvo pranešta apie kai kuriuos margos hipopigmentacijos atvejus kaip šalutinį LFQSNY poveikį, galbūt dėl didelės lazerio energijos. Agresyvus LFQSNY naudojimas taip pat gali sukelti hiperpigmentaciją dėl uždegimo, ypač esant tamsesniems odos atspalviams.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Recently, the low-fluence Q-switched Nd:YAG laser (LFQSNY) has been widely used for treating melasma, especially in Asia. It was hard to summarize the heterogenous studies, but LFQSNY appeared to be a generally effective and safe treatment for melasma considering the results of previous conventional therapies. However, mottled hypopigmentation has been occasionally reported to develop and persist as an adverse event of LFQSNY, which may be associated with the high accumulated laser energy. When used aggressively, even LFQSNY can induce hyperpigmentation via unwanted inflammation, especially in darker skin.
Pigmentacijos problemos dažnai nustatomos pirminėje sveikatos priežiūros srityje. Dažni hiperpigmentacijos sutrikimų tipai yra post-inflammatory hyperpigmentation, melasma, sunspots, freckles, and café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Pigmentation problems are often found in primary care. Common types of hyperpigmentation disorders include post-inflammatory hyperpigmentation, melasma, sunspots, freckles, café au lait spots.
Gydant lazeriu melazma tam tikrą laiką negali būti išgydyta, nes tai liga, kurios metu nuolat gaminasi pigmentas. Tranksenemo rūgštis padeda pagerinti pigmentaciją.
○ Gydymas
Kai kuriose šalyse (pvz., Japonijoje, Korėjoje) geriamoji traneksamo rūgštis yra prieinama be recepto ir yra veiksminga. Melasma kremas su traneksamo rūgštimi ir azelaino rūgštimi gali būti iš dalies naudingas.
Hidrochinonas gali būti naudojamas lokaliai hiperpigmentacijai gydyti, tačiau FDA sustabdė nereceptinius produktus, kurių sudėtyje yra hidrochinono nuo 2020 m.
#Tranexamic acid [TRANSINO]
#Laser toning technique (low fluence QS1064 laser)
#Triluma