Acanthosis nigricans
☆ 2022. gada Stiftung Warentest rezultātos no Vācijas patērētāju apmierinātība ar ModelDerm bija tikai nedaudz zemāka nekā ar maksas telemedicīnas konsultācijām.
Tas ir izplatīts cilvēkiem ar aptaukošanos.
References
Acanthosis nigricans ir pamatslimības ādas izpausme. Tas bieži parādās ādas krokās, piemēram, kaklā, padusēs un cirkšņos, izskatoties kā samtaini tumši plankumi ar neskaidrām malām. Šis stāvoklis parasti ir saistīts ar diabētu un insulīna rezistenci, bet retos gadījumos tas var norādīt uz vēzi organismā. Tas var parādīties arī hormonu problēmu vai noteiktu medikamentu, piemēram, steroīdu un kontracepcijas tablešu, lietošanas dēļ.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) ir izplatīta ādas slimība, kas saistīta ar dažādām veselības problēmām, piemēram, insulīna rezistenci, diabētu, aptaukošanos, noteiktiem vēža veidiem, hormonālām problēmām un reakcijām uz medikamentiem. AN ārstēšana ir vērsta uz pamatā esošo veselības problēmu risināšanu. Sākotnēji ārsti pārbauda insulīna rezistences sindroma pazīmes, kas ietver aptaukošanos, augstu holesterīna līmeni, augstu asinsspiedienu un 2. Tipa cukura diabētu. Ārsti bieži izraksta topical retinoids kā pirmo ārstēšanas izvēli, kas var palīdzēt ādas sabiezēšanai. Tomēr tie var pilnībā novērst ādas tumšumu. Arī citām ārstēšanas iespējām, piemēram, salicylic acid, podophyllin, urea, and calcipotriol , ir nepieciešama bieža lietošana.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ Causes
Tas parasti rodas personām, kas jaunākas par 40 gadiem, var būt ģenētiski iedzimtas un saistītas ar aptaukošanos vai endokrinopātijām, piemēram, hipotireozi, akromegāliju, policistisku olnīcu slimību, insulīnrezistentu diabētu vai Kušinga slimību.
○ Ārstēšana — ārpusbiržas zāles
#40% urea cream