Dysplastic nevus
☆ Tamin'ny valin'ny Stiftung Warentest 2022 avy any Alemaina, ny fahafaham-pon'ny mpanjifa amin'ny ModelDerm dia ambany kely noho ny fifampidinihana telemedicine karama.
Dysplastic nevi ― Ny biopsy dia atolotra ho an'ny Tandrefana.
References
Dysplastic nevus , fantatra amin'ny anarana hoe atypical na Clarks nevus, dia niteraka adihevitra momba ny dermatology sy ny dermatopathology. Matetika ny dokotera dia manao biopsy ireo molotra ireo satria mety tsy hita maso izy ireo ary miteraka ahiahy momba ny melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
A dysplastic nevus is also referred to as an atypical or Clarks nevus and has been the topic of much debate in the fields of dermatology and dermatopathology. It is an acquired mole demonstrating a unique clinical and histopathologic appearance that sets it apart from the common nevus. These moles appear atypical clinically, often with a fried-egg appearance, and are commonly biopsied by providers due to the concern for melanoma.
Dysplastic nevi , fantatra ihany koa amin'ny hoe atypical na Clark nevi, dia mety hitarika ho amin'ny melanoma indraindray. Manodidina ny 36% amin'ny melanoma no hita eo akaikin'ny nevi dysplastic. Ny famantarana fa mety hivadika ho melanoma ny nevus dysplastic dia ahitana endrika tsy mitovy, fiovan'ny pigment bebe kokoa, na loko volondavenona. Ireo kansera ireo dia matetika mitranga amin'ny taona kely (eo amin'ny tapaky ny telopolo taona eo ho eo) , mety ho maromaro, ary matetika eo amin'ny vatan-kazo. Amin'ny fototarazo, dysplastic nevi dia eo anelanelan'ny nevi malemy sy melanoma. Na izany aza, 20% hatramin'ny 30% amin'ny melanôma ihany no avy amin'ny nevi efa misy. Koa satria ny ankamaroan'ny nevi dia tsy lasa melanoma, matetika dia tsy soso-kevitra ny hanala azy ireo amin'ny fomba fisorohana.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Dysplastic nevus, also called atypical or Clark nevus, can be precursor to melanoma, as the observation that 36% of melanomas have dysplastic nevi near the invasive tumor supports. Signs that a dysplastic nevus may have transitioned into a melanoma include asymmetry in contour, a noticeable increase in pigment variations, or a grayish tint indicating regression. These malignancies typically arise at a younger age (mid-thirties), are sometimes multiple, and are often found on the trunk. Molecularly, dysplastic nevi have a profile intermediate between benign nevi and malignant melanoma. While there is a recognized connection between dysplastic nevi and melanoma, it’s crucial to note that only about 20% to 30% of melanomas evolve from preexisting nevi. Given that the majority of dysplastic and typical nevi do not develop into melanoma, preventive removal of melanocytic nevi is not typically advised.
Ny melanoma dia karazana fivontosana miforona rehefa lasa homamiadana ny melanocytes, sela tompon'andraikitra amin'ny lokon'ny hoditra. Ny melanocytes dia avy amin'ny crest neural. Midika izany fa tsy eo amin'ny hoditra ihany no mety hivoatra ny melanoma, fa any amin'ny faritra hafa izay ifindran'ny sela neural crest, toy ny taratasy mivalona amin'ny gastrointestinalina sy ny atidoha. Ny taham-pahavelomana ho an'ny marary voan'ny melanoma amin'ny dingana voalohany (dingana 0) dia ambony amin'ny 97%, raha toa ka midina be izany ho 10% ho an'ireo voan'ny aretina efa mandroso (stage IV) .
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin, can arise in other locations where neural crest cells migrate, such as the gastrointestinal tract and brain. The five-year relative survival rate for patients with stage 0 melanoma is 97%, compared with about 10% for those with stage IV disease.
○ Loza homamiadana
Araka ny hita amin'ny olona Caucasian any Etazonia, ireo manana dysplastic nevi dia manana risika mandritra ny androm-piainany ho voan'ny melanoma mihoatra ny 10%. Amin'ny lafiny iray, ireo izay tsy manana dysplastic nevus dia mety ho voan'ny melanoma latsaky ny 1%.
○ Fitandrina ny olona voan'ny dysplastic nevi
Ny fandinihan-tena amin'ny hoditra dia matetika no soso-kevitra amin'ny fisorohana ny melanoma (amin'ny famantarana ny nevi atypical azo esorina) na mba hamantarana mialoha ny fivontosana efa misy. Ny olona manana tantaram-pianakaviana voan'ny kanseran'ny hoditra na voan'ny nevi atypical maro dia tokony hanatona mpitsabo aretin-tsaina farafahakeliny indray mandeha isan-taona mba hahazoana antoka fa tsy voan'ny melanoma izy ireo.
Ny fanafohezana [ABCDE] dia nahasoa tamin'ny fanampiana ireo mpanome tolotra ara-pahasalamana sy laika hahatsiaro ireo toetra fototry ny melanoma. Indrisy ho an'ny olon-tsotra, maro ny seborrheic keratoses, ny sasany lentigo senilis, ary na ny warts aza dia mety manana toetra [ABCDE], ary tsy azo avahana amin'ny melanoma.
○ [ABCDE]
Asymmetrical: Fetin'ny hoditra tsy mifanitsy.
Border: Tsy ara-dalàna ny sisin'ny fery.
Color: Matetika ny melanoma dia manana loko tsy ara-dalàna maro.
Diameter: nevi lehibe kokoa noho ny 6 mm dia mety ho melanoma kokoa noho ny nevi kely kokoa.
Evolution: Ny fivoarana (izany hoe fiovàna) ny nevus na ny ratra dia mety manondro fa lasa masiaka ilay ratra.