Herpes simplex
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Herpes simplex amin'ny molotra.
Herpes simplex ― Ny aretina Herpes simplex amin'ny rantsantanana dia mahazatra kokoa amin'ny ankizy kely noho ny amin'ny olon-dehibe.
References
Ny fihanaky ny HSV-1 dia mandroso amin'ny alàlan'ny otrikaretina voalohany amin'ny sela epithelial, arahin'ny fahatarana, indrindra amin'ny neurons, ary ny famerenana indray. Ny HSV-1 dia matetika miteraka fipoahana vesicular voalohany sy miverimberina, indrindra eo amin'ny vava sy ny mucosa genital. Ny fisehoany dia manomboka amin'ny herpes orolabial amin'ny toe-javatra isan-karazany toy ny folliculitis herpetic, aretina amin'ny hoditra, fidiran'ny maso, ary tranga mahery vaika toy ny herpes encephalitis. Ny fitsaboana antiviral dia manampy amin'ny fitantanana ny fihanaky ny HSV.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 2 (HSV-2) dia areti-mifindra miparitaka be, mihatra amin'ny 22% amin'ny olon-dehibe 12 taona no ho miakatra, mitentina 45 tapitrisa ny olon-dehibe any Etazonia. Na dia miteraka fery am-bava aza ny HSV-1, dia mety miteraka fery amin'ny taovam-pananahana ihany koa izany. Na izany aza, rehefa voan'ny fery amin'ny taovam-pananahana ny marary, dia matetika ny HSV-2 no tena mampanahy. Ny soritr'aretin'ny fihanaky ny HSV-2 dia matetika manjavozavo, toy ny fivaviana sy ny fahasosorana, izay mety hanemotra ny fitiliana sy ny fitsaboana. Mety hiteraka fifindran'ny hafa amin'ny olona tsy voan'ny aretina io fahatarana io.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus (HSV) dia miteraka aretina toy ny herpes amin'ny taovam-pananahana sy ny fery mangatsiaka amin'ny zatovo sy ny olon-dehibe. Rehefa voan'ny HSV ny zaza ao anatin'ny 4-6 herinandro voalohany amin'ny fiainana, dia mety hiteraka aretina mafy izany ary misy vokany lehibe izany. Ny fitiliana haingana ny otrikaretina HSV amin'ny zaza vao teraka dia zava-dehibe mba hampitsaharana ny aretina tsy hiharatsy, hisorohana ny olana momba ny neurologique (eny fa na dia ny fahafatesana aza) .
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
Herpes simplex ny aretina dia tena fahita ary azo mifindra avy amin'ny vehivavy bevohoka amin'ny zanany. Ity virosy ity dia mety hiteraka olana ara-pahasalamana lehibe na fahafatesana mihitsy aza amin'ny zaza vao teraka. Na dia tsy fahita firy aza izany mandritra ny fitondrana vohoka, dia matetika mitranga izany mandritra ny fiterahana. Ny risika dia ambony indrindra raha voan'ny aretina ny reny amin'ny dingana farany amin'ny fitondrana vohoka. Na izany aza, io risika io dia azo ahena amin'ny fampiasana fanafody antiviral na misafidy ny fizarana C amin'ny toe-javatra sasany.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Ny Herpes simplex virus (HSV) karazana 1 sy 2 dia mamindra olona maro maneran-tany. Amin'ny ankapobeny, mijanona mangina ao amin'ny selan'ny nerve ilay viriosy rehefa avy niparitaka tamin'ny hoditra, saingy mety hihetsika indray izany any aoriana, ka miteraka fery mangatsiaka. Indraindray, miteraka olana goavana izany toy ny areti-maso, areti-maso, na toe-javatra mampidi-doza amin'ny zaza vao teraka sy ny olona manana hery fiarovana malemy. Na dia manampy amin'ny fifehezana otrikaretina aza ny fanafody amin'izao fotoana izao, dia mbola mampanahy ny mety hisian'ny fanoherana ny zava-mahadomelina sy ny voka-dratsiny. Mila fanafody vaovao isika mba hikendry tsara kokoa ny viriosy.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
Misy karazany roa ny viriosy herpes simplex , karazana 1 (HSV-1) ary karazana 2 (HSV-2). Ny HSV-1 dia matetika miteraka otrikaretina manodidina ny vava raha ny HSV-2 no miteraka aretina ara-pananahana. Afindra amin'ny fifandraisana mivantana amin'ilay olona voan'ny aretina izy ireo. Ny herpes genital dia sokajiana ho aretina azo avy amin'ny firaisana. Mety hiparitaka amin’ny zaza vao teraka izany. Aorian'ny otrikaretina, ny viriosy dia entina miaraka amin'ny nerveuse sensory mankany amin'ny vatan'ny selan'ny nerve, izay itoeran'izy ireo mandritra ny androm-piainana. Ny antony mahatonga ny fiverenana dia mety ahitana: ny fihenan'ny hery fiarovana, ny adin-tsaina ary ny fiposahan'ny masoandro.
Amin'ny ankabeazan'ny toe-javatra, ny fanafody antiviral dia tsy raisina raha tsy rehefa mafy ny soritr'aretina. Ny fanafody antiviral isan'andro dia azo omena ny olona voan'ny aretina matetika. Tsy misy vaksiny azo ary tsy misoroka ny herpes simplex ny vaksinin'ny shingles. Ny fitsaboana amin'ny fanafody antiviral toy ny aciclovir na valaciclovir dia mety hampihena ny hamafin'ny soritr'aretina.
Ny tahan'ny HSV-1 na HSV-2 manerantany dia eo anelanelan'ny 60% sy 95% amin'ny olon-dehibe. Ny HSV-1 dia matetika voan'ny aretina mandritra ny fahazazana. Tombanana ho 536 tapitrisa ny olona eran-tany (16%-n'ny mponina) voan'ny HSV-2 tamin'ny taona 2003 ary betsaka kokoa ny tahan'ny vehivavy sy ny any amin'ny tany an-dalam-pandrosoana. Ny ankamaroan'ny olona manana HSV-2 dia tsy mahatsapa fa voan'ny aretina izy ireo.
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