Prurigo nodularis
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References
Prurigo nodularis dia toetry ny hoditry ny hoditra maharitra maharitra ny fivontosana sy ny nodules, matetika hita amin'ny faritra ivelan'ny sandry sy tongotra. Mety tsy hitovy ny lokon'ireny bongo ireny manomboka amin'ny lokon'ny nofo ka hatramin'ny mavokely ary mangidihidy mafy. Mety hisy fiantraikany amin'ny olona amin'ny taona rehetra izy ireo ary matetika mifandray amin'ny aretina hoditra hafa izay miteraka mangidihidy maharitra, toy ny dermatitis atopika. Ny safidy amin'ny fitsaboana dia ahitana fanafody mahery manohitra ny mangidihidy, fanafody misy fiantraikany amin'ny hery fiarovana, ary fanafody mikendry ny rafi-pitatitra. Ny fitantanana ny prurigo nodularis dia matetika mitaky fitsaboana maharitra.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Prurigo nodularis is a chronic disorder of the skin that is classically seen as multiple, firm, flesh to pink colored papules, plaques and nodules commonly located on the extensor surfaces of the extremities. The lesions are very pruritic and can occur in any age group. It is commonly associated with another disease such as atopic dermatitis or any dermatoses associated with chronic pruritus. The therapeutic approach is wide-arrayed ranging from treatments that act as - potent antipruritics, immunomodulators, and neuromodulators. Treatment in an established case is prolonged and improving patient compliance with education and counseling is important.
Matetika ny fitsaboana dia mampiasa crème na tsindrona steroïde amin'ny faritra voakasika. Amin'ny toe-javatra mafy kokoa na mafy loha, dia mety ilaina ny fitsaboana toy ny fitsaboana maivana na fanafody manafoana ny hery fiarovana. Thalidomide sy lenalidomide dia safidy ho an'ny tranga mafy, saingy mety hisy fiantraikany ratsy. Ny fitsaboana vaovao (opioid receptor antagonists, neurokinin-1 receptor antagonists) dia mampiseho fampanantenana amin'ny fitsaboana prurigo nodularis miaraka amin'ny voka-dratsiny vitsy kokoa raha oharina amin'ny thalidomide na lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Treatment typically relies on the use of topical or intralesional steroids, though more severe or recalcitrant cases often necessitate the use of phototherapy or systemic immunosuppressives. Thalidomide and lenalidomide can both be used in severe cases; however, their toxicity profile makes them less favorable. Opioid receptor antagonists and neurokinin-1 receptor antagonists represent two novel families of therapeutic agents which may effectively treat PN with a lower toxicity profile than thalidomide or lenalidomide.
Chronic prurigo dia toetry ny hoditra misy mangidihidy maharitra (maharitra 6 herinandro mahery) , ratra amin'ny hoditra mifandray amin'ny rangotra, ary tantara mikisaka matetika. Tafiditra ao anatin'izany ny neuroinflammation sy fibrosis amin'ny hoditra.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated pruriginous skin lesions and history of repeated scratching.
Ny Prurigo nodularis dia olana amin'ny hoditra maharitra, voamarika amin'ny nodules mangidihidy. Tsy fantatsika mazava tsara ny antony mahatonga izany, fa toa ny olana amin'ny immune sy nerveuse dia manana anjara toerana amin'ny tsingerin'ny mangidihidy. Amin'izao fotoana izao, tsy misy fitsaboana ankatoavin'ny US FDA manokana ho an'ny prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
Prurigo nodularis is a long-lasting skin problem marked by itchy nodules. We don't know exactly what causes it, but it seems that immune and nerve issues play a role in the itch-scratch cycle. Right now, there aren't any treatments approved by the US FDA specifically for prurigo nodularis.
○ Fitsaboana - Fanafody OTC
Ny fanasana ny faritra misy lesoka amin'ny savony dia tsy manampy mihitsy ary mety hiharatsy izany. Ny menaka steroid OTC dia mety hanampy amin'ny fanalefahana ny soritr'aretina, saingy matetika izy ireo dia mila ampiharina mandritra ny herinandro maromaro mba hihatsara. Manampy amin'ny fanalefahana ny mangidihidy koa ny fanohizana ny fihinanana antihistamines.
#OTC steroid ointment
#OTC antihistamine
○ Fitsaboana
#Intralesional triamcinolone injection